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Neutron experiments helped reveal the one-carbon enzymatic mechanism that synthesizes vital food sources for cancer cells that depend on vitamin B6, providing key insights into designing novel drugs to slow the spread of aggressive cancers. Credit: Jill Hemman/ORNL, U.S. Dept. of Energy

After a highly lauded research campaign that successfully redesigned a hepatitis C drug into one of the leading drug treatments for COVID-19, scientists at ORNL are now turning their drug design approach toward cancer. 

Credit: NAIC Arecibo Observatory, a facility of the NSF; (INSET) Michelle Negron, National Science Foundation

For more than half a century, the 1,000-foot-diameter spherical reflector dish at the Arecibo Observatory in Puerto Rico was the largest radio telescope in the world. Completed in 1963, the dish was built in a natural sinkhole, with the telescope’s feed antenna suspended 500 feet above the dish on a 1.8-million-pound steel platform. Three concrete towers and more than 4 miles of steel cables supported the platform.

Credit: Genevieve Martin/ORNL, U.S. Dept. of Energy

After completing a bachelor’s degree in biology, Toya Beiswenger didn’t intend to go into forensics. But almost two decades later, the nuclear security scientist at ORNL has found a way to appreciate the art of nuclear forensics.

Clouds of gray smoke in the lower left are funneled northward from wildfires in Western Canada, reaching the edge of the sea ice covering the Arctic Ocean. A second path of thick smoke is visible at the top center of the image, emanating from wildfires in the boreal areas of Russia’s Far East, in this image captured on July 13, 2023. Credit: NASA MODIS

Wildfires have shaped the environment for millennia, but they are increasing in frequency, range and intensity in response to a hotter climate. The phenomenon is being incorporated into high-resolution simulations of the Earth’s climate by scientists at the Department of Energy’s Oak Ridge National Laboratory, with a mission to better understand and predict environmental change.

Two researchers standing back to back in a grassy area

When geoinformatics engineering researchers at the Department of Energy’s Oak Ridge National Laboratory wanted to better understand changes in land areas and points of interest around the world, they turned to the locals — their data, at least.

Upgrades to the particle accelerator enabling the record 1.7-megawatt beam power at the Spallation Neutron Source included adding 28 high-power radio-frequency klystrons (red tubes) to provide higher power for the accelerator. Credit: Genevieve Martin/ORNL, U.S. Dept. of Energy

The Spallation Neutron Source at the Department of Energy's Oak Ridge National Laboratory set a world record when its particle accelerator beam operating power reached 1.7 megawatts, substantially improving on the facility’s original design capability.

Researchers at the Department of Energy’s Oak Ridge National Laboratory were the first to use neutron reflectometry to peer inside a working solid-state battery and monitor its electrochemistry.

Researchers at the Department of Energy’s Oak Ridge National Laboratory were the first to use neutron reflectometry to peer inside a working solid-state battery and monitor its electrochemistry.

Tristen Mullins. Credit: Carlos Jones/ORNL, U.S. Dept. of Energy

Tristen Mullins enjoys the hidden side of computers. As a signals processing engineer for ORNL, she tries to uncover information hidden in components used on the nation’s power grid — information that may be susceptible to cyberattacks.

Herwig shared the impacts of neutron science with Secretary of Energy Jennifer Granholm during a tour of SNS in November 2021. Credit: Carlos Jones/ORNL, U.S. Dept. of Energy

Ken Herwig's scientific drive crystallized in his youth when he solved a tough algebra word problem in his head while tossing newspapers from his bicycle. He said the joy he felt in that moment as a teenager fueled his determination to conquer mathematical mysteries. And he did.

ORNL’s Yun Liu stands before one of the 10 laser comb-based beam diagnostics stations at the Spallation Neutron Source. The laser comb solves the longstanding problem of measuring changes in the beam across time. Credit: Genevieve Martin/ORNL, U.S. Dept. of Energy

When opportunity meets talent, great things happen. The laser comb developed at ORNL serves as such an example.