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ORNL researchers led by Michael Garvin, left, and David Kainer discovered genetic mutations called structural variants and linked them to autism spectrum disorders, demonstrating an approach that could be used to develop better diagnostics and drug therapies. Credit: Carlos Jones/ORNL, U.S. Dept. of Energy

ORNL researchers discovered genetic mutations that underlie autism using a new approach that could lead to better diagnostics and drug therapies.

Researchers at ORNL designed a recyclable carbon fiber material to promote low-carbon manufacturing. Credit: Chad Malone/ORNL, U.S. Dept. of Energy

Oak Ridge National Laboratory scientists designed a recyclable polymer for carbon-fiber composites to enable circular manufacturing of parts that boost energy efficiency in automotive, wind power and aerospace applications.

Researchers used quantum Monte Carlo calculations to accurately render the structure and electronic properties of germanium selenide, a semiconducting nanomaterial. Credit: Paul Kent/ORNL, U.S. Dept. of Energy

A multi-lab research team led by ORNL's Paul Kent is developing a computer application called QMCPACK to enable precise and reliable predictions of the fundamental properties of materials critical in energy research.

Oak Ridge National Laboratory researchers developed an invertible neural network, a type of artificial intelligence that mimics the human brain, to improve accuracy in climate-change models and predictions. Credit: Getty Images

Oak Ridge National Laboratory researchers developed an invertible neural network, a type of artificial intelligence that mimics the human brain, to improve accuracy in climate-change models and predictions.

With seismic and acoustic data recorded by remote sensors near ORNL’s High Flux Isotope Reactor, researchers could predict whether the reactor was on or off with 98% accuracy. Credit: Nathan Armistead/ORNL, U.S. Dept. of Energy

An Oak Ridge National Laboratory team developed a novel technique using sensors to monitor seismic and acoustic activity and machine learning to differentiate operational activities at facilities from “noise” in the recorded data.

Virginia-based battery technology company, BTRY, has licensed several electrolyte and thin-film coating technologies, developed at Oak Ridge National Laboratory, to make batteries with increased energy density, at lower cost, and with an improved safety profile in crashes. Credit: Carlos Jones/ORNL, U.S. Dept. of Energy

Several electrolyte and thin-film coating technologies, developed at Oak Ridge National Laboratory, have been licensed by BTRY, a battery technology company based in Virginia, to make batteries with increased energy density, at lower cost, and with an improved safety profile in crashes.

Researchers at Oak Ridge National Laboratory demonstrated center-of-mass scanning transmission electron microscopy to observe lithium along with heavier elements in battery materials at atomic resolution. Credit: Chad Malone/ORNL, U.S. Dept. of Energy

Oak Ridge National Laboratory researchers demonstrated an electron microscopy technique for imaging lithium in energy storage materials, such as lithium ion batteries, at the atomic scale.

ORNL researchers worked with partners at the Colorado School of Mines and Baylor University to develop a new process optimization and control method for a closed-circuit reverse osmosis desalination system. The work is intended to support fully automated, decentralized water treatment plants. Credit: Andrew Sproles/ORNL, U.S. Dept. of Energy

Oak Ridge National Laboratory scientists worked with the Colorado School of Mines and Baylor University to develop and test control methods for autonomous water treatment plants that use less energy and generate less waste.

Samples of four unique materials hitched a ride to space as part of an effort by ORNL scientists to evaluate how each fares under space conditions. Credit: Zac Ward/ORNL, U.S. Dept. of Energy

To study how space radiation affects materials for spacecraft and satellites, Oak Ridge National Laboratory scientists sent samples to the International Space Station. The results will inform design of radiation-resistant magnetic and electronic systems.

ORNL’s Eva Zarkadoula seeks piezoelectric materials for sensors that can withstand irradiation, which causes cascading collisions that displace atoms and produces defects. Credit: Carlos Jones/ORNL, U.S. Dept. of Energy

To advance sensor technologies, Oak Ridge National Laboratory researchers studied piezoelectric materials, which convert mechanical stress into electrical energy, to see how they could handle bombardment with energetic neutrons.