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With seismic and acoustic data recorded by remote sensors near ORNL’s High Flux Isotope Reactor, researchers could predict whether the reactor was on or off with 98% accuracy. Credit: Nathan Armistead/ORNL, U.S. Dept. of Energy

An Oak Ridge National Laboratory team developed a novel technique using sensors to monitor seismic and acoustic activity and machine learning to differentiate operational activities at facilities from “noise” in the recorded data.

Genetic analysis revealed connections between inflammatory activity and development of atomic dermatitis, according to researchers from the UPenn School of Medicine, the Perelman School of Medicine, and Oak Ridge National Laboratory. Credit: Kang Ko/UPenn

University of Pennsylvania researchers called on computational systems biology expertise at Oak Ridge National Laboratory to analyze large datasets of single-cell RNA sequencing from skin samples afflicted with atopic dermatitis.

A new process developed by Oak Ridge National Laboratory leverages deep learning techniques to study cell movements in a simulated environment, guided by simple physics rules similar to video-game play. Credit: MSKCC and UTK

Scientists have developed a novel approach to computationally infer previously undetected behaviors within complex biological environments by analyzing live, time-lapsed images that show the positioning of embryonic cells in C. elegans, or roundworms. Their published methods could be used to reveal hidden biological activity. 

self-healing elastomers
Researchers at Oak Ridge National Laboratory developed self-healing elastomers that demonstrated unprecedented adhesion strength and the ability to adhere to many surfaces, which could broaden their potential use
An X-ray CT image of a 3D-printed metal turbine blade was reconstructed using ORNL’s neural network and advanced algorithms. Credit: Amir Ziabari/ORNL, U.S. Dept. of Energy

Algorithms developed at Oak Ridge National Laboratory can greatly enhance X-ray computed tomography images of 3D-printed metal parts, resulting in more accurate, faster scans.

Fungi use signaling molecules called LCOs to communicate with each other and to regulate growth. Credit: Jessy Labbe/Oak Ridge National Laboratory, U.S. Dept. of Energy

Oak Ridge National Laboratory and collaborators have discovered that signaling molecules known to trigger symbiosis between plants and soil bacteria are also used by almost all fungi as chemical signals to communicate with each other.

ORNL assisted in investigating proteins called porins, one shown in red, which are found in the protective outer membrane of certain disease-causing bacteria and tether the membrane to the cell wall. Credit: Hyea (Sunny) Hwang/Georgia Tech and ORNL, U.S. Dept. of Energy

Scientists from Oak Ridge National Laboratory used high-performance computing to create protein models that helped reveal how the outer membrane is tethered to the cell membrane in certain bacteria.

Shown here is an on-chip carbonized electrode microstructure from a scanning electron microscope. Credit: ORNL, U.S. Dept. of Energy

Scientists at Oak Ridge National Laboratory and the University of Tennessee designed and demonstrated a method to make carbon-based materials that can be used as electrodes compatible with a specific semiconductor circuitry.

Simulation of short polymer chains

Oak Ridge National Laboratory scientists have discovered a cost-effective way to significantly improve the mechanical performance of common polymer nanocomposite materials.

Cars and coronavirus

Oak Ridge National Laboratory researchers have developed a machine learning model that could help predict the impact pandemics such as COVID-19 have on fuel demand in the United States.