Skip to main content
ORNL researchers led by Michael Garvin, left, and David Kainer discovered genetic mutations called structural variants and linked them to autism spectrum disorders, demonstrating an approach that could be used to develop better diagnostics and drug therapies. Credit: Carlos Jones/ORNL, U.S. Dept. of Energy

ORNL researchers discovered genetic mutations that underlie autism using a new approach that could lead to better diagnostics and drug therapies.

Fungi use signaling molecules called LCOs to communicate with each other and to regulate growth. Credit: Jessy Labbe/Oak Ridge National Laboratory, U.S. Dept. of Energy

Oak Ridge National Laboratory and collaborators have discovered that signaling molecules known to trigger symbiosis between plants and soil bacteria are also used by almost all fungi as chemical signals to communicate with each other.

ORNL assisted in investigating proteins called porins, one shown in red, which are found in the protective outer membrane of certain disease-causing bacteria and tether the membrane to the cell wall. Credit: Hyea (Sunny) Hwang/Georgia Tech and ORNL, U.S. Dept. of Energy

Scientists from Oak Ridge National Laboratory used high-performance computing to create protein models that helped reveal how the outer membrane is tethered to the cell membrane in certain bacteria.

Smart Neighborhood homes

To better determine the potential energy cost savings among connected homes, researchers at Oak Ridge National Laboratory developed a computer simulation to more accurately compare energy use on similar weather days.

Motion sensing technology

Oak Ridge National Laboratory is training next-generation cameras called dynamic vision sensors, or DVS, to interpret live information—a capability that has applications in robotics and could improve autonomous vehicle sensing.

Computing—Building a brain

Researchers at Oak Ridge National Laboratory are taking inspiration from neural networks to create computers that mimic the human brain—a quickly growing field known as neuromorphic computing.

Computing—Routing out the bugs

A study led by Oak Ridge National Laboratory explored the interface between the Department of Veterans Affairs’ healthcare data system and the data itself to detect the likelihood of errors and designed an auto-surveillance tool

Using artificial intelligence, Oak Ridge National Laboratory analyzed data from published medical studies to reveal the potential of direct and indirect impacts of bullying.

Oak Ridge National Laboratory is using artificial intelligence to analyze data from published medical studies associated with bullying to reveal the potential of broader impacts, such as mental illness or disease.