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Genetic analysis revealed connections between inflammatory activity and development of atomic dermatitis, according to researchers from the UPenn School of Medicine, the Perelman School of Medicine, and Oak Ridge National Laboratory. Credit: Kang Ko/UPenn

University of Pennsylvania researchers called on computational systems biology expertise at Oak Ridge National Laboratory to analyze large datasets of single-cell RNA sequencing from skin samples afflicted with atopic dermatitis.

ORNL has modeled the spike protein that binds the novel coronavirus to a human cell for better understanding of the dynamics of COVID-19. Credit: Stephan Irle/ORNL, U.S. Dept. of Energy

To better understand the spread of SARS-CoV-2, the virus that causes COVID-19, Oak Ridge National Laboratory researchers have harnessed the power of supercomputers to accurately model the spike protein that binds the novel coronavirus to a human cell receptor.

The TRITON model provides a detailed visualization of the flooding that resulted when Hurricane Harvey stalled over Houston for four days in 2017. Credit: Mario Morales-Hernández/ORNL, U.S. Dept. of Energy

A new tool from Oak Ridge National Laboratory can help planners, emergency responders and scientists visualize how flood waters will spread for any scenario and terrain.

Computing – Mining for COVID-19 connections

Scientists have tapped the immense power of the Summit supercomputer at Oak Ridge National Laboratory to comb through millions of medical journal articles to identify potential vaccines, drugs and effective measures that could suppress or stop the

This simulation of a fusion plasma calculation result shows the interaction of two counter-streaming beams of super-heated gas. Credit: David L. Green/Oak Ridge National Laboratory, U.S. Dept. of Energy

The prospect of simulating a fusion plasma is a step closer to reality thanks to a new computational tool developed by scientists in fusion physics, computer science and mathematics at ORNL.

Tungsten tiles for fusion

Using additive manufacturing, scientists experimenting with tungsten at Oak Ridge National Laboratory hope to unlock new potential of the high-performance heat-transferring material used to protect components from the plasma inside a fusion reactor. Fusion requires hydrogen isotopes to reach millions of degrees.

An ORNL-developed graphite foam, which could be used in plasma-facing components in fusion reactors, performed well during testing at the Wendlestein 7-X stellarator in Germany.

Scientists have tested a novel heat-shielding graphite foam, originally created at Oak Ridge National Laboratory, at Germany’s Wendelstein 7-X stellarator with promising results for use in plasma-facing components of fusion reactors.

At the salt–metal interface, thermodynamic forces drive chromium from the bulk of a nickel alloy, leaving a porous, weakened layer. Impurities in the salt drive further corrosion of the structural material. Credit: Stephen Raiman/Oak Ridge National Labora

Oak Ridge National Laboratory scientists analyzed more than 50 years of data showing puzzlingly inconsistent trends about corrosion of structural alloys in molten salts and found one factor mattered most—salt purity.