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Seeing the difference Ac-225 could make to cancer patients made Raina Setzer want to come to ORNL to directly work with the isotope. Credit: Allison Peacock/ORNL, U.S. Dept. of Energy

Raina Setzer knows the work she does matters. That’s because she’s already seen it from the other side. Setzer, a radiochemical processing technician in Oak Ridge National Laboratory’s Isotope Processing and Manufacturing Division, joined the lab in June 2023.

Researchers at Oak Ridge National Laboratory probed the chemistry of radium to gain key insights on advancing cancer treatments using radiation therapy. Credit: Adam Malin/ORNL, U.S. Dept. of Energy

Researchers at ORNL explored radium’s chemistry to advance cancer treatments using ionizing radiation.

Mars Rover 2020

More than 50 current employees and recent retirees from ORNL received Department of Energy Secretary’s Honor Awards from Secretary Jennifer Granholm in January as part of project teams spanning the national laboratory system. The annual awards recognized 21 teams and three individuals for service and contributions to DOE’s mission and to the benefit of the nation.

An algorithm developed and field-tested by ORNL researchers uses machine learning to maintain homeowners’ preferred temperatures year-round while minimizing energy costs. Credit: ORNL, U.S. Dept. of Energy

Oak Ridge National Laboratory researchers designed and field-tested an algorithm that could help homeowners maintain comfortable temperatures year-round while minimizing utility costs.

Targeted alpha therapy can deliver radiation to specific cells, with minimal effect on surrounding, healthy cells. Credit: Michelle Lehman and Jaimee Janiga/ORNL, U.S. Dept. of Energy

A rare isotope in high demand for treating cancer is now more available to pharmaceutical companies developing and testing new drugs.

ORNL welder Devin Johnson uses a new orbital welder to seal a hollow target in a glovebox in the lab’s Radiochemical Engineering Development Center. The new welder makes a clean seam on the metal target, eliminating the need for hand-finishing afterward. Credit: Carlos Jones/ORNL, U.S. Dept. of Energy

A better way of welding targets for Oak Ridge National Laboratory’s plutonium-238 production has sped up the process and improved consistency and efficiency. This advancement will ultimately benefit the lab’s goal to make enough Pu-238 – the isotope that powers NASA’s deep space missions – to yield 1.5 kilograms of plutonium oxide annually by 2026.

Sandra Davern performs cell based assays to evaluate cell death and DNA damage in response to radiation in order to gain a better understanding of how radioisotope nanoparticles affect the human body.

When Sandra Davern looks to the future, she sees individualized isotopes sent into the body with a specific target: cancer cells.

Smart Neighborhood homes

To better determine the potential energy cost savings among connected homes, researchers at Oak Ridge National Laboratory developed a computer simulation to more accurately compare energy use on similar weather days.

quantum mechanics to advance a range of technologies including computing, fiber optics and network communication

Three researchers at Oak Ridge National Laboratory will lead or participate in collaborative research projects aimed at harnessing the power of quantum mechanics to advance a range of technologies including computing, fiber optics and network