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ORNL scientists developed a method that improves the accuracy of the CRISPR Cas9 gene editing tool used to modify microbes for renewable fuels and chemicals production. This research draws on the lab’s expertise in quantum biology, artificial intelligence and synthetic biology. Credit: Philip Gray/ORNL, U.S. Dept. of Energy

Scientists at ORNL used their expertise in quantum biology, artificial intelligence and bioengineering to improve how CRISPR Cas9 genome editing tools work on organisms like microbes that can be modified to produce renewable fuels and chemicals.

Seeing the difference Ac-225 could make to cancer patients made Raina Setzer want to come to ORNL to directly work with the isotope. Credit: Allison Peacock/ORNL, U.S. Dept. of Energy

Raina Setzer knows the work she does matters. That’s because she’s already seen it from the other side. Setzer, a radiochemical processing technician in Oak Ridge National Laboratory’s Isotope Processing and Manufacturing Division, joined the lab in June 2023.

Ken Engle portrait

It was reading about current nuclear discoveries in textbooks that first made Ken Engle want to work at a national lab. It was seeing the real-world impact of the isotopes produced at ORNL 

 

ytterbium

ORNL’s electromagnetic isotope separator, or EMIS, made history in 2018 when it produced 500 milligrams of the rare isotope ruthenium-96, unavailable anywhere else in the world. 

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Growing up in suburban Upper East Tennessee, Layla Marshall didn’t see a lot of STEM opportunities for children. 
“I like encouraging young people to get involved in the kinds of things I’ve been doing in my career,” said Marshall. “I like seeing the students achieve their goals. It’s fun to watch them get excited about learning new things and teaching the robot to do things that they didn’t know it could do until they tried it.”
Marshall herself has a passion for learning new things. 

An AI-generated image representing atoms and artificial neural networks. Credit: Maxim Ziatdinov, ORNL

Researchers at ORNL have developed a machine-learning inspired software package that provides end-to-end image analysis of electron and scanning probe microscopy images.

Oak Ridge National Laboratory led a team of scientists to design a molecule that disrupts the infection mechanism of the SARS-CoV-2 coronavirus and could be used to develop new treatments for COVID-19 and future virus outbreaks. Credit: Michelle Lehman/ORNL, U.S. Dept. of Energy

A team of scientists led by the Department of Energy’s Oak Ridge National Laboratory designed a molecule that disrupts the infection mechanism of the SARS-CoV-2 coronavirus and could be used to develop new treatments for COVID-19 and other viral diseases.

Jason Gardner, Sandra Davern and Peter Thornton have been elected fellows of AAAS. Credit: Laddy Fields/ORNL, U.S. Dept. of Energy

Three scientists from the Department of Energy’s Oak Ridge National Laboratory have been elected fellows of the American Association for the Advancement of Science, or AAAS.

A team led by Raymond Borges Hink has developed a method using blockchain to protect communications between electronic devices in the electric grid, preventing cyberattacks and cascading blackouts. Credit: Genevieve Martin/ORNL, U.S. Dept. of Energy

Although blockchain is best known for securing digital currency payments, researchers at the Department of Energy’s Oak Ridge National Laboratory are using it to track a different kind of exchange: It’s the first time blockchain has ever been used to validate communication among devices on the electric grid.

Thomaz Carvalhaes. Credit: Carlos Jones/ORNL, U.S. Dept. of Energy

In human security research, Thomaz Carvalhaes says, there are typically two perspectives: technocentric and human centric. Rather than pick just one for his work, Carvalhaes uses data from both perspectives to understand how technology impacts the lives of people.