Skip to main content
Neutron experiments helped reveal the one-carbon enzymatic mechanism that synthesizes vital food sources for cancer cells that depend on vitamin B6, providing key insights into designing novel drugs to slow the spread of aggressive cancers. Credit: Jill Hemman/ORNL, U.S. Dept. of Energy

After a highly lauded research campaign that successfully redesigned a hepatitis C drug into one of the leading drug treatments for COVID-19, scientists at ORNL are now turning their drug design approach toward cancer. 

ORNL’s Fernanda Santos examines a soil sample at an NGEE Arctic field site in the Alaskan tundra in June 2022. Credit: Amy Breen, University of Alaska Fairbanks.

Wildfires are an ancient force shaping the environment, but they have grown in frequency, range and intensity in response to a changing climate. At ORNL, scientists are working on several fronts to better understand and predict these events and what they mean for the carbon cycle and biodiversity.

Upgrades to the particle accelerator enabling the record 1.7-megawatt beam power at the Spallation Neutron Source included adding 28 high-power radio-frequency klystrons (red tubes) to provide higher power for the accelerator. Credit: Genevieve Martin/ORNL, U.S. Dept. of Energy

The Spallation Neutron Source at the Department of Energy's Oak Ridge National Laboratory set a world record when its particle accelerator beam operating power reached 1.7 megawatts, substantially improving on the facility’s original design capability.

ORNL’s Debangshu Mukherjee was named an npj Computational Materials “Reviewer of the Year.”

ORNL’s Debangshu Mukherjee has been named an npj Computational Materials “Reviewer of the Year.”

Matt Sieger. Credit: Carlos Jones/ORNL

The Oak Ridge Leadership Computing Facility’s Matt Sieger has been named the project director for the OLCF-6 effort. This next OLCF undertaking will plan and build a world-class successor to the OLCF’s still-new exascale system, Frontier.

ORNL’s Shih-Chieh Kao has been named a 2023 fellow of the American Society of Civil Engineers’ Environmental & Water Resources Institute. Credit: Carlos Jones/ORNL, U.S. Dept. of Energy

Shih-Chieh Kao, manager of the Water Power program at ORNL, has been named a fellow of the American Society of Civil Engineer’s Environmental & Water Resources Institute, or EWRI.

Colleen Iversen is the new director of NGEE Arctic, leading a large cross-disciplinary team of scientists in pursuit of a better understanding of Arctic climate processes. Credit: ORNL, U.S. Dept. of Energy

Colleen Iversen, ecosystem ecologist, group leader and distinguished staff scientist, has been named director of the Next-Generation Ecosystem Experiments Arctic, or NGEE Arctic, a multi-institutional project studying permafrost thaw and other climate-related processes in Alaska.

Computing pioneer Jack Dongarra has been elected to the National Academy of Sciences.

Computing pioneer Jack Dongarra has been elected to the National Academy of Sciences in recognition of his distinguished and continuing achievements in original research.

Xiao Wang

Xiao Wang, a research scientist at ORNL, has been named a senior member of the Institute of Electrical and Electronics Engineers, the world’s largest organization for technical professionals. Wang works in the lab’s Computing and Computational Sciences Directorate’s Advanced Computing for Health Sciences Section.

UKAEA will provide novel fusion materials to be irradiated in ORNL’s HFIR facility over the next four years. From left, Kathy McCarthy, Jeremy Busby, Mickey Wade, Prof Sir Ian Chapman (UKAEA CEO), Cynthia Jenks and Yutai Kato will represent this new partnership. Not pictured: Dr. Amanda Quadling, UKAEA’s Director of Materials Research Facility. Credit: Genevieve Martin/ORNL, U.S. Dept. of Energy

ORNL has entered a strategic research partnership with the United Kingdom Atomic Energy Authority, or UKAEA, to investigate how different types of materials behave under the influence of high-energy neutron sources. The $4 million project is part of UKAEA's roadmap program, which aims to produce electricity from fusion.