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ORNL scientists developed a method that improves the accuracy of the CRISPR Cas9 gene editing tool used to modify microbes for renewable fuels and chemicals production. This research draws on the lab’s expertise in quantum biology, artificial intelligence and synthetic biology. Credit: Philip Gray/ORNL, U.S. Dept. of Energy

Scientists at ORNL used their expertise in quantum biology, artificial intelligence and bioengineering to improve how CRISPR Cas9 genome editing tools work on organisms like microbes that can be modified to produce renewable fuels and chemicals.

When exposed to radiation, electrons produced within molten zinc chloride, or ZnCl2, can be observed in three distinct singly occupied molecular orbital states, plus a more diffuse, delocalized state. Credit: Hung H. Nguyen/University of Iowa

In a finding that helps elucidate how molten salts in advanced nuclear reactors might behave, scientists have shown how electrons interacting with the ions of the molten salt can form three states with different properties. Understanding these states can help predict the impact of radiation on the performance of salt-fueled reactors.

The OpeN-AM experimental platform, installed at the VULCAN instrument at ORNL’s Spallation Neutron Source, features a robotic arm that prints layers of molten metal to create complex shapes. This allows scientists to study 3D printed welds microscopically. Credit: Jill Hemman, ORNL/U.S. Dept. of Energy

Using neutrons to see the additive manufacturing process at the atomic level, scientists have shown that they can measure strain in a material as it evolves and track how atoms move in response to stress.

ORNL’s David Sholl is director of the new DOE Energy Earthshot Non-Equilibrium Energy Transfer for Efficient Reactions center to help decarbonize the industrial chemical industry. Credit: Genevieve Martin, ORNL/U.S. Dept. of Energy

ORNL has been selected to lead an Energy Earthshot Research Center, or EERC, focused on developing chemical processes that use sustainable methods instead of burning fossil fuels to radically reduce industrial greenhouse gas emissions to stem climate change and limit the crisis of a rapidly warming planet.
 

Construction is underway at ORNL's Spallation Neutron Source. Credit: The Spallation Neutron Source at Oak Ridge National Laboratory — already the world’s most powerful accelerator-based neutron source — will be on a planned hiatus through June 2024 as crews work to upgrade the facility. Credit: Brett Riffert/ORNL, U.S. Dept. of Energy

The Spallation Neutron Source — already the world’s most powerful accelerator-based neutron source — will be on a planned hiatus through June 2024 as crews work to upgrade the facility. Much of the work — part of the facility’s Proton Power Upgrade project — will involve building a connector between the accelerator and the planned Second Target Station.

The OpeN-AM experimental platform, installed at the VULCAN instrument, features a robotic arm that prints layers of molten metal to create complex shapes. Credit: Jill Hemman/ORNL, U.S Dept. of Energy

Technologies developed by researchers at ORNL have received six 2023 R&D 100 Awards.  

Bryan Maldonado, a researcher in the Buildings and Transportation Science Division at ORNL, will receive the 2023 Most Promising Engineer Award from the Hispanic Engineer National Achievements Awards Conference. Credit: ORNL, U.S. Dept. of Energy

Bryan Maldonado, a dynamic systems and controls researcher at ORNL, has been recognized by the 2023 Hispanic Engineer National Achievements Awards Conference, or HENAAC, with the Most Promising Engineer Award.  

Neutron experiments helped reveal the one-carbon enzymatic mechanism that synthesizes vital food sources for cancer cells that depend on vitamin B6, providing key insights into designing novel drugs to slow the spread of aggressive cancers. Credit: Jill Hemman/ORNL, U.S. Dept. of Energy

After a highly lauded research campaign that successfully redesigned a hepatitis C drug into one of the leading drug treatments for COVID-19, scientists at ORNL are now turning their drug design approach toward cancer. 

Innovation Crossroads cohort 7

Seven entrepreneurs will embark on a two-year fellowship as the seventh cohort of Innovation Crossroads kicks off this month at ORNL. Representing a range of transformative energy technologies, Cohort 7 is a diverse class of innovators with promising new companies.

Upgrades to the particle accelerator enabling the record 1.7-megawatt beam power at the Spallation Neutron Source included adding 28 high-power radio-frequency klystrons (red tubes) to provide higher power for the accelerator. Credit: Genevieve Martin/ORNL, U.S. Dept. of Energy

The Spallation Neutron Source at the Department of Energy's Oak Ridge National Laboratory set a world record when its particle accelerator beam operating power reached 1.7 megawatts, substantially improving on the facility’s original design capability.