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Neutron experiments helped reveal the one-carbon enzymatic mechanism that synthesizes vital food sources for cancer cells that depend on vitamin B6, providing key insights into designing novel drugs to slow the spread of aggressive cancers. Credit: Jill Hemman/ORNL, U.S. Dept. of Energy

After a highly lauded research campaign that successfully redesigned a hepatitis C drug into one of the leading drug treatments for COVID-19, scientists at ORNL are now turning their drug design approach toward cancer. 

ORNL’s Fernanda Santos examines a soil sample at an NGEE Arctic field site in the Alaskan tundra in June 2022. Credit: Amy Breen, University of Alaska Fairbanks.

Wildfires are an ancient force shaping the environment, but they have grown in frequency, range and intensity in response to a changing climate. At ORNL, scientists are working on several fronts to better understand and predict these events and what they mean for the carbon cycle and biodiversity.

Upgrades to the particle accelerator enabling the record 1.7-megawatt beam power at the Spallation Neutron Source included adding 28 high-power radio-frequency klystrons (red tubes) to provide higher power for the accelerator. Credit: Genevieve Martin/ORNL, U.S. Dept. of Energy

The Spallation Neutron Source at the Department of Energy's Oak Ridge National Laboratory set a world record when its particle accelerator beam operating power reached 1.7 megawatts, substantially improving on the facility’s original design capability.

TIP graphic

Scientist-inventors from ORNL will present seven new technologies during the Technology Innovation Showcase on Friday, July 14, from 8 a.m.–4 p.m. at the Joint Institute for Computational Sciences on ORNL’s campus.

ORNL researchers have enabled standard raised pavement markers to transmit GPS information that helps autonomous driving features function better in remote areas or in bad weather. Credit: Carlos Jones/ORNL, U.S. Dept. of Energy

Working with Western Michigan University and other partners, ORNL engineers are placing low-powered sensors in the reflective raised pavement markers that are already used to help drivers identify lanes. Microchips inside the markers transmit information to passing cars about the road shape to help autonomous driving features function even when vehicle cameras or remote laser sensing, called LiDAR, are unreliable because of fog, snow, glare or other obstructions.

Exascale Computing Project

Lawrence Livermore National Laboratory’s Lori Diachin will take over as director of the Department of Energy’s Exascale Computing Project on June 1, guiding the successful, multi-institutional high-performance computing effort through its final stages.

Robert Wagner

SAE International has awarded ORNL Buildings and Transportation Science Division Director Robert Wagner with the SAE Medal of Honor for his dedication and support of the organization’s mission of advancing mobility solutions.

Michael Parks

ORNL has named Michael Parks director of the Computer Science and Mathematics Division within ORNL’s Computing and Computational Sciences Directorate. His hiring became effective March 13.

Mickey Wade

Mickey Wade has been named associate laboratory director for the Fusion and Fission Energy and Science Directorate at the Department of Energy’s Oak Ridge National Laboratory, effective April 1.

A new license to U2opia pairs two technologies developed in ORNL’s Cyber Resilience and Intelligence Division: Situ and Heartbeat. Credit: ORNL, U.S. Dept. of Energy

U2opia Technology, a consortium of technology and administrative executives with extensive experience in both industry and defense, has exclusively licensed two technologies from ORNL that offer a new method for advanced cybersecurity monitoring in real time.