Skip to main content
Neutron experiments helped reveal the one-carbon enzymatic mechanism that synthesizes vital food sources for cancer cells that depend on vitamin B6, providing key insights into designing novel drugs to slow the spread of aggressive cancers. Credit: Jill Hemman/ORNL, U.S. Dept. of Energy

After a highly lauded research campaign that successfully redesigned a hepatitis C drug into one of the leading drug treatments for COVID-19, scientists at ORNL are now turning their drug design approach toward cancer. 

Mirko Musa was always fascinated by the power of rivers, specifically how these mighty waterways sculpt landscapes. Now, as a water power researcher, he’s finding ways to harness that power and protect rivers at the same time. Credit: Carlos Jones/ORNL, U.S. Dept. of Energy

Mirko Musa spent his childhood zigzagging his bike along the Po River. The Po, Italy’s longest river, cuts through a lush valley of grain and vegetable fields, which look like a green and gold ocean spreading out from the river’s banks. 

Upgrades to the particle accelerator enabling the record 1.7-megawatt beam power at the Spallation Neutron Source included adding 28 high-power radio-frequency klystrons (red tubes) to provide higher power for the accelerator. Credit: Genevieve Martin/ORNL, U.S. Dept. of Energy

The Spallation Neutron Source at the Department of Energy's Oak Ridge National Laboratory set a world record when its particle accelerator beam operating power reached 1.7 megawatts, substantially improving on the facility’s original design capability.

Saubhagya Rathore uses his modeling, hydrology and engineering expertise to improve understanding of the nation’s watersheds to better predict the future climate and to guide resilience strategies. Credit: Genevieve Martin/ORNL, U.S. Dept. of Energy

Growing up exploring the parklands of India where Rudyard Kipling drew inspiration for The Jungle Book left Saubhagya Rathore with a deep respect and curiosity about the natural world. He later turned that interest into a career in environmental science and engineering, and today he is working at ORNL to improve our understanding of watersheds for better climate prediction and resilience.

Herwig shared the impacts of neutron science with Secretary of Energy Jennifer Granholm during a tour of SNS in November 2021. Credit: Carlos Jones/ORNL, U.S. Dept. of Energy

Ken Herwig's scientific drive crystallized in his youth when he solved a tough algebra word problem in his head while tossing newspapers from his bicycle. He said the joy he felt in that moment as a teenager fueled his determination to conquer mathematical mysteries. And he did.

Frontier supercomputer

Innovations in artificial intelligence are rapidly shaping our world, from virtual assistants and chatbots to self-driving cars and automated manufacturing.

ORNL seismic researcher Chengping Chai placed seismic sensors on the ground at various distances from an ORNL nuclear reactor to learn whether they could detect its operating state. Credit: Carlos Jones/ORNL, U.S. Dept. of Energy

Like most scientists, Chengping Chai is not content with the surface of things: He wants to probe beyond to learn what’s really going on. But in his case, he is literally building a map of the world beneath, using seismic and acoustic data that reveal when and where the earth moves.

ORNL researchers, from left, Yang Liu, Xiaohan Yang and Torik Islam, collaborated on the development of a new capability to insert multiple genes simultaneously for fast, efficient transformation of plants into better bioenergy feedstocks. Credit: Genevieve Martin/ORNL, U.S. Dept. of Energy

In a discovery aimed at accelerating the development of process-advantaged crops for jet biofuels, scientists at ORNL developed a capability to insert multiple genes into plants in a single step.

Ashley Barker. Credit: Carlos Jones/ORNL

At the National Center for Computational Sciences, Ashley Barker enjoys one of the least complicated–sounding job titles at ORNL: section head of operations. But within that seemingly ordinary designation lurks a multitude of demanding roles as she oversees the complete user experience for NCCS computer systems.

Matt Sieger. Credit: Carlos Jones/ORNL

The Oak Ridge Leadership Computing Facility’s Matt Sieger has been named the project director for the OLCF-6 effort. This next OLCF undertaking will plan and build a world-class successor to the OLCF’s still-new exascale system, Frontier.