Skip to main content
Samantha Peters co-designed and conducted experiments using ORNL’s high-performance mass spectrometry techniques to prove that bacteriophages deploy genetic code-switching to overwhelm and destroy host bacteria. Credit: Genevieve Martin, ORNL/U.S. Dept. of Energy

Scientists at ORNL have confirmed that bacteria-killing viruses called bacteriophages deploy a sneaky tactic when targeting their hosts: They use a standard genetic code when invading bacteria, then switch to an alternate code at later stages of

Philipe Ambrozio Dias. Credit: Genevieve Martin/ORNL, U.S. Dept. of Energy

Having lived on three continents spanning the world’s four hemispheres, Philipe Ambrozio Dias understands the difficulties of moving to a new place.

Conduit hydropower presents opportunities in every state. Credit: ORNL, U.S. Dept. of Energy

Millions of miles of pipelines and conduits across the United States make up an intricate network of waterways used for municipal, agricultural and industrial purposes.

ORNL’s Tomás Rush explores the secret lives of fungi and plants for insights into the interactions that determine plant health. Credit: Genevieve Martin/ORNL, U.S. Dept. of Energy

Tomás Rush began studying the mysteries of fungi in fifth grade and spent his college intern days tromping through forests, swamps and agricultural lands searching for signs of fungal plant pathogens causing disease on host plants.

ORNL is studying how climate change may impact water availability for hydropower facilities such as the Shasta Dam and Lake in California. Credit: U.S. Bureau of Reclamation

ORNL has provided hydropower operators with new data to better prepare for extreme weather events and shifts in seasonal energy demands caused by climate change.

Thomaz Carvalhaes. Credit: Carlos Jones/ORNL, U.S. Dept. of Energy

In human security research, Thomaz Carvalhaes says, there are typically two perspectives: technocentric and human centric. Rather than pick just one for his work, Carvalhaes uses data from both perspectives to understand how technology impacts the lives of people.

Shown here is the structure of the NEMO protein. A team from ORNL conducted extensive molecular dynamics work on Summit by using both quantum mechanics and machine-learning methods to look at the binding affinity of NEMO and 3CLpro in humans and other species and to consider the structural models derived from the sequences of other coronaviruses. Image courtesy Nature Communications, Dan Jacobson/ORNL.

A new paper published in Nature Communications adds further evidence to the bradykinin storm theory of COVID-19’s viral pathogenesis — a theory that was posited two years ago by a team of researchers at the Department of Energy’s Oak Ridge National Laboratory.

Data from different sources are joined on platforms created by ORNL researchers to offer better information for decision makers. Credit: ORNL/Nathan Armistead

When the COVID-19 pandemic stunned the world in 2020, researchers at ORNL wondered how they could extend their support and help

ORNL identity science researcher Nell Barber works on a facial recognition camera. Credit: Genevieve Martin/ORNL, U.S. Dept. of Energy

Though Nell Barber wasn’t sure what her future held after graduating with a bachelor’s degree in psychology, she now uses her interest in human behavior to design systems that leverage machine learning algorithms to identify faces in a crowd.

Logan Sturm, Alvin M. Weinberg Fellow at ORNL, creates a mashup between additive manufacturing and cybersecurity research. Credit: Carlos Jones/ORNL, U.S. Dept. of Energy

How an Alvin M. Weinberg Fellow is increasing security for critical infrastructure components