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![Image of outerspace](/sites/default/files/styles/list_page_thumbnail/public/2023-04/Dark%20Matter%20Thumbnail.png?h=c673cd1c&itok=vaZLUOBP)
Few things carry the same aura of mystery as dark matter. The name itself radiates secrecy, suggesting something hidden in the shadows of the Universe.
![Andrea Delgado, Distinguished Staff Fellow at Oak Ridge National Laboratory, uses quantum computing to help elucidate the fundamental particles of the universe. Credit: Carlos Jones/ORNL, U.S. Dept. of Energy](/sites/default/files/styles/list_page_thumbnail/public/2023-04/Andrea%20Delgado%20Thumbnail.png?h=c6980913&itok=PSWgGpfa)
Andrea Delgado is looking for elementary particles that seem so abstract, there appears to be no obvious short-term benefit to her research.
![Frances Pleasonton seals a vacuum chamber in 1951.](/sites/default/files/styles/list_page_thumbnail/public/2023-03/Pleasonton20616_16x9_1678989753589_0.jpg?h=d1cb525d&itok=s-itGaqM)
The old photos show her casually writing data in a logbook with stacks of lead bricks nearby, or sealing a vacuum chamber with a wrench. ORNL researcher Frances Pleasonton was instrumental in some of the earliest explorations of the properties of the neutron as the X-10 Site was finding its postwar footing as a research lab.
![Vincente Guiseppe, co-spokesperson of the Majorana Collaboration and a research staff member at ORNL, in front of the Majorana Demonstrator shield on the 4850 Level of SURF. Credit: Nick Hubbard/Sanford Underground Research Facility](/sites/default/files/styles/list_page_thumbnail/public/2023-03/2-MJD-Guiseppe%20in%20front%20of%20shield_4.jpeg?h=a141e9ea&itok=URbl8Trd)
For nearly six years, the Majorana Demonstrator quietly listened to the universe. Nearly a mile underground at the Sanford Underground Research Facility, or SURF, in Lead, South Dakota, the experiment collected data that could answer one of the most perplexing questions in physics: Why is the universe filled with something instead of nothing?
![From left are UWindsor students Isabelle Dib, Dominik Dziura, Stuart Castillo and Maksymilian Dziura at ORNL’s Neutron Spin Echo spectrometer. Their work advances studies on a natural cancer treatment. Credit: Genevieve Martin/ORNL, U.S. Dept. of Energy](/sites/default/files/styles/list_page_thumbnail/public/2023-03/2022-P14758_0.jpg?h=c6980913&itok=YJLFDsPp)
A scientific instrument at ORNL could help create a noninvasive cancer treatment derived from a common tropical plant.
![Shown here is the structure of the NEMO protein. A team from ORNL conducted extensive molecular dynamics work on Summit by using both quantum mechanics and machine-learning methods to look at the binding affinity of NEMO and 3CLpro in humans and other species and to consider the structural models derived from the sequences of other coronaviruses. Image courtesy Nature Communications, Dan Jacobson/ORNL.](/sites/default/files/styles/list_page_thumbnail/public/2022-09/bradykinin_1.png?h=53873e96&itok=iBwJwFaV)
A new paper published in Nature Communications adds further evidence to the bradykinin storm theory of COVID-19’s viral pathogenesis — a theory that was posited two years ago by a team of researchers at the Department of Energy’s Oak Ridge National Laboratory.
![Oak Ridge National Laboratory’s Mitch Allmond works with the Facility for Rare Isotope Beams Decay Station initiator, which combined diverse detectors for FRIB’s first experiment. Credit: Robert Grzywacz/ORNL, U.S. Dept. of Energy](/sites/default/files/styles/list_page_thumbnail/public/2022-06/FRIB1.jpg?h=429981e8&itok=sFq0uTlk)
Two decades in the making, a new flagship facility for nuclear physics opened on May 2, and scientists from the Department of Energy’s Oak Ridge National Laboratory have a hand in 10 of its first 34 experiments.
![ORNL, VA and Harvard researchers developed a sparse matrix full of anonymized information on what is thought to be the largest cohort of healthcare data used for this type of research in the U.S. The matrix can be probed with different methods, such as KESER, to gain new insights into human health. Credit: Nathan Armistead/ORNL, U.S. Dept. of Energy](/sites/default/files/styles/list_page_thumbnail/public/2022-04/2022-G00330_KESER%20Illustration_0.jpg?h=1cb48fc4&itok=c6ZuDdDg)
A team of researchers has developed a novel, machine learning–based technique to explore and identify relationships among medical concepts using electronic health record data across multiple healthcare providers.
![Oak Ridge National Laboratory researchers used an invertible neural network, a type of artificial intelligence that mimics the human brain, to select the most suitable materials for desired properties, such as flexibility or heat resistance, with high chemical accuracy. The study could lead to more customizable materials design for industry.](/sites/default/files/styles/list_page_thumbnail/public/2022-04/CCSD_NeuralNetworkBanner.png?h=b16f811b&itok=fxqDEvs_)
A study led by researchers at ORNL could help make materials design as customizable as point-and-click.
![Earth Day](/sites/default/files/styles/list_page_thumbnail/public/2022-04/Earth%20image.png?h=8f74817f&itok=5rQ_su9Z)
Tackling the climate crisis and achieving an equitable clean energy future are among the biggest challenges of our time.