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Media Contacts
![An ORNL-led team comprising researchers from multiple DOE national laboratories is using artificial intelligence and computational screening techniques – in combination with experimental validation – to identify and design five promising drug therapy approaches to target the SARS-CoV-2 virus. Credit: Michelle Lehman/ORNL, U.S. Dept. of Energy](/sites/default/files/styles/list_page_thumbnail/public/2021-06/frame1.png?h=d1cb525d&itok=51pwBWyP)
An ORNL-led team comprising researchers from multiple DOE national laboratories is using artificial intelligence and computational screening techniques – in combination with experimental validation – to identify and design five promising drug therapy approaches to target the SARS-CoV-2 virus.
![Frontier supercomputer](/sites/default/files/styles/list_page_thumbnail/public/2023-01/frontier_0.jpg?h=a1e1a043&itok=J3IM_Xeh)
A multi-institutional team, led by a group of investigators at Oak Ridge National Laboratory, has been studying various SARS-CoV-2 protein targets, including the virus’s main protease. The feat has earned the team a finalist nomination for the Association of Computing Machinery, or ACM, Gordon Bell Special Prize for High Performance Computing-Based COVID-19 Research.
![Suman Debnath is using simulation algorithms to accelerate understanding of the modern power grid and enhance its reliability and resilience. Credit: Carlos Jones/ORNL, U.S. Dept. of Energy](/sites/default/files/styles/list_page_thumbnail/public/2021-01/Suman%20Debnath%20Square.jpg?h=439d043c&itok=1umME5uH)
Planning for a digitized, sustainable smart power grid is a challenge to which Suman Debnath is using not only his own applied mathematics expertise, but also the wider communal knowledge made possible by his revival of a local chapter of the IEEE professional society.
![Enzyme activity during organophosphate poisoning](/sites/default/files/styles/list_page_thumbnail/public/2020-08/anecdote1_0.png?h=d1cb525d&itok=wpYYilBI)
Pick your poison. It can be deadly for good reasons such as protecting crops from harmful insects or fighting parasite infection as medicine — or for evil as a weapon for bioterrorism. Or, in extremely diluted amounts, it can be used to enhance beauty.
![The hybrid inverter developed by ORNL is an intelligent power electronic inverter platform that can connect locally sited energy resources such as solar panels, energy storage and electric vehicles and interact efficiently with the utility power grid. Credit: Carlos Jones, ORNL/U.S. Dept of Energy.](/sites/default/files/styles/list_page_thumbnail/public/2020-07/2020-P09169.jpg?h=42d56c10&itok=Yb1_gWYE)
ORNL researchers have developed an intelligent power electronic inverter platform that can connect locally sited energy resources such as solar panels, energy storage and electric vehicles and smoothly interact with the utility power grid.
![Computational biophysicist Ada Sedova is using experiments and high-performance computing to explore the properties of biological systems and predict their form and function, including research to accelerate drug discovery for COVID-19. Photo credit: Jason Richards, Oak Ridge National Laboratory, U.S. Dept. of Energy.](/sites/default/files/styles/list_page_thumbnail/public/2020-07/2017-P06162Cropped.jpg?h=f1d4573a&itok=TrvR_opt)
Ada Sedova’s journey to Oak Ridge National Laboratory has taken her on the path from pre-med studies in college to an accelerated graduate career in mathematics and biophysics and now to the intersection of computational science and biology
![Oak Ridge National Laboratory researchers demonstrated on Feb. 27 a 20-kilowatt, bi-directional wireless charging system on a medium-class hybrid electric delivery truck. Credit: Brittany Cramer/Oak Ridge National Laboratory, U.S. Dept. of Energy](/sites/default/files/styles/list_page_thumbnail/public/2020-04/UPS%20Demo%20rear%20view_0.jpg?h=d6078784&itok=SOL9HQ_c)
Researchers at the Department of Energy’s Oak Ridge National Laboratory (ORNL) in late February demonstrated a 20-kilowatt bi-directional wireless charging system installed on a UPS medium-duty, plug-in hybrid electric delivery truck.
![Coronavirus graphic](/sites/default/files/styles/list_page_thumbnail/public/2020-04/covid19_jh_0.png?h=d1cb525d&itok=PyngFUZw)
In the race to identify solutions to the COVID-19 pandemic, researchers at the Department of Energy’s Oak Ridge National Laboratory are joining the fight by applying expertise in computational science, advanced manufacturing, data science and neutron science.
![Scientists created a novel polymer that is as effective as natural proteins in transporting protons through a membrane. Credit: ORNL/Jill Hemman](/sites/default/files/styles/list_page_thumbnail/public/2020-03/19-G01195_nature_feature_0.png?h=e4fbc3eb&itok=K8czXmTr)
Biological membranes, such as the “walls” of most types of living cells, primarily consist of a double layer of lipids, or “lipid bilayer,” that forms the structure, and a variety of embedded and attached proteins with highly specialized functions, including proteins that rapidly and selectively transport ions and molecules in and out of the cell.
![The image visualizes how the team’s multitask convolutional neural network classifies primary cancer sites. Image credit: Hong-Jun Yoon/ORNL](/sites/default/files/styles/list_page_thumbnail/public/2020-02/shot_0.png?h=49ab6177&itok=IXL5Ingy)
As the second-leading cause of death in the United States, cancer is a public health crisis that afflicts nearly one in two people during their lifetime.