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Seeing the difference Ac-225 could make to cancer patients made Raina Setzer want to come to ORNL to directly work with the isotope. Credit: Allison Peacock/ORNL, U.S. Dept. of Energy

Raina Setzer knows the work she does matters. That’s because she’s already seen it from the other side. Setzer, a radiochemical processing technician in Oak Ridge National Laboratory’s Isotope Processing and Manufacturing Division, joined the lab in June 2023.

Plutonium oxide is loaded onto a truck for shipping. Adam Parkison/ORNL, U.S. Dept. of Energy

In June, ORNL hit a milestone not seen in more than three decades: producing a production-quality amount of plutonium-238

JungHyun Bae portrait

JungHyun Bae is a nuclear scientist studying applications of particles that have some beneficial properties: They are everywhere, they are unlimited, they are safe.

A researcher works in a lab in the Radiochemical Engineering and Development Center, or REDC,  at ORNL’s main campus. The REDC provides world-class capabilities in isotope production, research and development, source fabrication, and the distribution of various unique isotopes. Here, experts handle some of the most exotic materials in the world. Credit: Carlos Jones, ORNL/U.S. Dept. of Energy

A series of new classes at Pellissippi State Community College will offer students a new career path — and a national laboratory a pipeline of workers who have the skills needed for its own rapidly growing programs.

Stephen Dahunsi. Credit: Jason Richards/ORNL, U.S. Dept. of Energy

Stephen Dahunsi’s desire to see more countries safely deploy nuclear energy is personal. Growing up in Nigeria, he routinely witnessed prolonged electricity blackouts as a result of unreliable energy supplies. It’s a problem he hopes future generations won’t have to experience.

ORNL’s Tyler Spano examines a sample of uranyl nitrate solution that she uses as a precursor to many uranium oxide syntheses. Credit: Carlos Jones/ORNL, U.S. Dept. of Energy

The word “exotic” may not spark thoughts of uranium, but Tyler Spano’s investigations of exotic phases of uranium are bringing new knowledge to the nuclear nonproliferation industry.

Researchers at Oak Ridge National Laboratory probed the chemistry of radium to gain key insights on advancing cancer treatments using radiation therapy. Credit: Adam Malin/ORNL, U.S. Dept. of Energy

Researchers at ORNL explored radium’s chemistry to advance cancer treatments using ionizing radiation.

The ORNL researchers’ findings may enable better detection of uranium tetrafluoride hydrate, a little-studied byproduct of the nuclear fuel cycle, and better understanding of how environmental conditions influence the chemical behavior of fuel cycle materials. Credit: Kevin Pastoor/Colorado School of Mines

ORNL researchers used the nation’s fastest supercomputer to map the molecular vibrations of an important but little-studied uranium compound produced during the nuclear fuel cycle for results that could lead to a cleaner, safer world.

ORNL, VA and Harvard researchers developed a sparse matrix full of anonymized information on what is thought to be the largest cohort of healthcare data used for this type of research in the U.S. The matrix can be probed with different methods, such as KESER, to gain new insights into human health. Credit: Nathan Armistead/ORNL, U.S. Dept. of Energy

A team of researchers has developed a novel, machine learning–based  technique to explore and identify relationships among medical concepts using electronic health record data across multiple healthcare providers.

Summer Widner, Stephanie Timbs, James Gaugler and James Avenell of ORNL are part of a team that processes thorium-228, a byproduct of actinium-227. As new uses for thorium are realized, particularly in medicine, the lab expects the demand for the radioisotope to grow.

As a medical isotope, thorium-228 has a lot of potential — and Oak Ridge National Laboratory produces a lot.