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Seeing the difference Ac-225 could make to cancer patients made Raina Setzer want to come to ORNL to directly work with the isotope. Credit: Allison Peacock/ORNL, U.S. Dept. of Energy

Raina Setzer knows the work she does matters. That’s because she’s already seen it from the other side. Setzer, a radiochemical processing technician in Oak Ridge National Laboratory’s Isotope Processing and Manufacturing Division, joined the lab in June 2023.

This diagram demonstrates how a concentrating solar thermal plant could use molten salts to store solar energy that could later be used to generate electricity. Credit: Jaimee Janiga/ORNL, U.S. Dept. of Energy

Oak Ridge National Laboratory scientists recently demonstrated a low-temperature, safe route to purifying molten chloride salts that minimizes their ability to corrode metals. This method could make the salts useful for storing energy generated from the sun’s heat.

Researchers at Oak Ridge National Laboratory probed the chemistry of radium to gain key insights on advancing cancer treatments using radiation therapy. Credit: Adam Malin/ORNL, U.S. Dept. of Energy

Researchers at ORNL explored radium’s chemistry to advance cancer treatments using ionizing radiation.

The ORNL researchers’ findings may enable better detection of uranium tetrafluoride hydrate, a little-studied byproduct of the nuclear fuel cycle, and better understanding of how environmental conditions influence the chemical behavior of fuel cycle materials. Credit: Kevin Pastoor/Colorado School of Mines

ORNL researchers used the nation’s fastest supercomputer to map the molecular vibrations of an important but little-studied uranium compound produced during the nuclear fuel cycle for results that could lead to a cleaner, safer world.

ORNL, VA and Harvard researchers developed a sparse matrix full of anonymized information on what is thought to be the largest cohort of healthcare data used for this type of research in the U.S. The matrix can be probed with different methods, such as KESER, to gain new insights into human health. Credit: Nathan Armistead/ORNL, U.S. Dept. of Energy

A team of researchers has developed a novel, machine learning–based  technique to explore and identify relationships among medical concepts using electronic health record data across multiple healthcare providers.

Summer Widner, Stephanie Timbs, James Gaugler and James Avenell of ORNL are part of a team that processes thorium-228, a byproduct of actinium-227. As new uses for thorium are realized, particularly in medicine, the lab expects the demand for the radioisotope to grow.

As a medical isotope, thorium-228 has a lot of potential — and Oak Ridge National Laboratory produces a lot.

Sandra Davern performs cell based assays to evaluate cell death and DNA damage in response to radiation in order to gain a better understanding of how radioisotope nanoparticles affect the human body.

When Sandra Davern looks to the future, she sees individualized isotopes sent into the body with a specific target: cancer cells.

This photo shows the interior of the vessel of the General Atomics DIII-D National Fusion Facility in San Diego, where ORNL researchers are testing the suitability of tungsten to armor the inside of a fusion device. Credit: General Atomics

The inside of future nuclear fusion energy reactors will be among the harshest environments ever produced on Earth. What’s strong enough to protect the inside of a fusion reactor from plasma-produced heat fluxes akin to space shuttles reentering Earth’s atmosphere?

ORNL’s Drew Elliott served as a major collaborator in upgrading the Princeton Plasma Physics Laboratory’s Lithium Tokamak Experiment-Beta. Credit: Robert Kaita, Princeton Plasma Physics Laboratory

Lithium, the silvery metal that powers smart phones and helps treat bipolar disorders, could also play a significant role in the worldwide effort to harvest on Earth the safe, clean and virtually limitless fusion energy that powers the sun and stars.

ORNL scientists are currently using Proto-MPEX to perform necessary research and development that is needed to build MPEX. Credit: Genevieve Martin/Oak Ridge National Laboratory, U.S. Dept. of Energy

Temperatures hotter than the center of the sun. Magnetic fields hundreds of thousands of times stronger than the earth’s. Neutrons energetic enough to change the structure of a material entirely.