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Media Contacts
![Frances Pleasonton seals a vacuum chamber in 1951.](/sites/default/files/styles/list_page_thumbnail/public/2023-03/Pleasonton20616_16x9_1678989753589_0.jpg?h=d1cb525d&itok=s-itGaqM)
The old photos show her casually writing data in a logbook with stacks of lead bricks nearby, or sealing a vacuum chamber with a wrench. ORNL researcher Frances Pleasonton was instrumental in some of the earliest explorations of the properties of the neutron as the X-10 Site was finding its postwar footing as a research lab.
![Vincente Guiseppe, co-spokesperson of the Majorana Collaboration and a research staff member at ORNL, in front of the Majorana Demonstrator shield on the 4850 Level of SURF. Credit: Nick Hubbard/Sanford Underground Research Facility](/sites/default/files/styles/list_page_thumbnail/public/2023-03/2-MJD-Guiseppe%20in%20front%20of%20shield_4.jpeg?h=a141e9ea&itok=URbl8Trd)
For nearly six years, the Majorana Demonstrator quietly listened to the universe. Nearly a mile underground at the Sanford Underground Research Facility, or SURF, in Lead, South Dakota, the experiment collected data that could answer one of the most perplexing questions in physics: Why is the universe filled with something instead of nothing?
![Researchers at Oak Ridge National Laboratory probed the chemistry of radium to gain key insights on advancing cancer treatments using radiation therapy. Credit: Adam Malin/ORNL, U.S. Dept. of Energy](/sites/default/files/styles/list_page_thumbnail/public/2022-09/radium_0.jpg?h=dbdf53bf&itok=dMlhyVKO)
Researchers at ORNL explored radium’s chemistry to advance cancer treatments using ionizing radiation.
![Oak Ridge National Laboratory’s Mitch Allmond works with the Facility for Rare Isotope Beams Decay Station initiator, which combined diverse detectors for FRIB’s first experiment. Credit: Robert Grzywacz/ORNL, U.S. Dept. of Energy](/sites/default/files/styles/list_page_thumbnail/public/2022-06/FRIB1.jpg?h=429981e8&itok=sFq0uTlk)
Two decades in the making, a new flagship facility for nuclear physics opened on May 2, and scientists from the Department of Energy’s Oak Ridge National Laboratory have a hand in 10 of its first 34 experiments.
![ORNL, VA and Harvard researchers developed a sparse matrix full of anonymized information on what is thought to be the largest cohort of healthcare data used for this type of research in the U.S. The matrix can be probed with different methods, such as KESER, to gain new insights into human health. Credit: Nathan Armistead/ORNL, U.S. Dept. of Energy](/sites/default/files/styles/list_page_thumbnail/public/2022-04/2022-G00330_KESER%20Illustration_0.jpg?h=1cb48fc4&itok=c6ZuDdDg)
A team of researchers has developed a novel, machine learning–based technique to explore and identify relationships among medical concepts using electronic health record data across multiple healthcare providers.
![Genetic analysis revealed connections between inflammatory activity and development of atomic dermatitis, according to researchers from the UPenn School of Medicine, the Perelman School of Medicine, and Oak Ridge National Laboratory. Credit: Kang Ko/UPenn](/sites/default/files/styles/list_page_thumbnail/public/2022-02/Graves-AD_0.jpg?h=46d8a70d&itok=77AW7Swv)
University of Pennsylvania researchers called on computational systems biology expertise at Oak Ridge National Laboratory to analyze large datasets of single-cell RNA sequencing from skin samples afflicted with atopic dermatitis.
![An ORNL-led team studied the SARS-CoV-2 spike protein in the trimer state, shown here, to pinpoint structural transitions that could be disrupted to destabilize the protein and negate its harmful effects. Credit: Debsindhu Bhowmik/ORNL, U.S. Dept. of Energy](/sites/default/files/styles/list_page_thumbnail/public/2022-01/sars_cov_2_bk.png?h=05c2797f&itok=jQ2D9aTr)
To explore the inner workings of severe acute respiratory syndrome coronavirus 2, or SARS-CoV-2, researchers from ORNL developed a novel technique.
![An ORNL-led team comprising researchers from multiple DOE national laboratories is using artificial intelligence and computational screening techniques – in combination with experimental validation – to identify and design five promising drug therapy approaches to target the SARS-CoV-2 virus. Credit: Michelle Lehman/ORNL, U.S. Dept. of Energy](/sites/default/files/styles/list_page_thumbnail/public/2021-06/frame1.png?h=d1cb525d&itok=51pwBWyP)
An ORNL-led team comprising researchers from multiple DOE national laboratories is using artificial intelligence and computational screening techniques – in combination with experimental validation – to identify and design five promising drug therapy approaches to target the SARS-CoV-2 virus.
![The Perseverance rover](/sites/default/files/styles/list_page_thumbnail/public/2020-07/pia23492_0.jpg?h=d1cb525d&itok=A5U6cgBE)
On Feb. 18, the world will be watching as NASA’s Perseverance rover makes its final descent into Jezero Crater on the surface of Mars. Mars 2020 is the first NASA mission that uses plutonium-238 produced at the Department of Energy’s Oak Ridge National Laboratory.
![The researchers embedded a programmable model into a D-Wave quantum computer chip. Credit: D-Wave](/sites/default/files/styles/list_page_thumbnail/public/2021-02/P5-o5czF_0.jpg?h=b69e0e0e&itok=wCU6WIp_)
Since the 1930s, scientists have been using particle accelerators to gain insights into the structure of matter and the laws of physics that govern our world.