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Neutron experiments helped reveal the one-carbon enzymatic mechanism that synthesizes vital food sources for cancer cells that depend on vitamin B6, providing key insights into designing novel drugs to slow the spread of aggressive cancers. Credit: Jill Hemman/ORNL, U.S. Dept. of Energy

After a highly lauded research campaign that successfully redesigned a hepatitis C drug into one of the leading drug treatments for COVID-19, scientists at ORNL are now turning their drug design approach toward cancer. 

Innovation Crossroads cohort 7

Seven entrepreneurs will embark on a two-year fellowship as the seventh cohort of Innovation Crossroads kicks off this month at ORNL. Representing a range of transformative energy technologies, Cohort 7 is a diverse class of innovators with promising new companies.

Upgrades to the particle accelerator enabling the record 1.7-megawatt beam power at the Spallation Neutron Source included adding 28 high-power radio-frequency klystrons (red tubes) to provide higher power for the accelerator. Credit: Genevieve Martin/ORNL, U.S. Dept. of Energy

The Spallation Neutron Source at the Department of Energy's Oak Ridge National Laboratory set a world record when its particle accelerator beam operating power reached 1.7 megawatts, substantially improving on the facility’s original design capability.

TIP graphic

Scientist-inventors from ORNL will present seven new technologies during the Technology Innovation Showcase on Friday, July 14, from 8 a.m.–4 p.m. at the Joint Institute for Computational Sciences on ORNL’s campus.

Jun Qu of ORNL shows stainless-steel disks

Scientists at ORNL have invented a coating that could dramatically reduce friction in common load-bearing systems with moving parts, from vehicle drive trains to wind

Stan David, retired ORNL scientist, has received the Joining and Welding Science Award.

Stan David, retired scientist and Corporate Fellow Emeritus at the Department of Energy’s Oak Ridge National Laboratory, was awarded the Joining and Welding Science Award from the Joining and Welding Research Institute at Osaka University, Japan.

Rigoberto Advincula

Rigoberto Advincula, a renowned scientist at ORNL and professor of Chemical and Biomolecular Engineering at the University of Tennessee, has won the Netzsch North American Thermal Analysis Society Fellows Award for 2023.

ORNL’s Debangshu Mukherjee was named an npj Computational Materials “Reviewer of the Year.”

ORNL’s Debangshu Mukherjee has been named an npj Computational Materials “Reviewer of the Year.”

Exascale Computing Project

Lawrence Livermore National Laboratory’s Lori Diachin will take over as director of the Department of Energy’s Exascale Computing Project on June 1, guiding the successful, multi-institutional high-performance computing effort through its final stages.

ORNL researchers Michael Smith, Steven Pain and Kelly Chipps use JENSA, a unique gas jet system, for laboratory studies of nuclear reactions that also occur in neutron stars in binary systems. Credit: Steven Pain/ORNL, U.S. Dept. of Energy

Led by Kelly Chipps of ORNL, scientists working in the lab have produced a signature nuclear reaction that occurs on the surface of a neutron star gobbling mass from a companion star. Their achievement improves understanding of stellar processes generating diverse nuclear isotopes.