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Frances Pleasonton seals a vacuum chamber in 1951.

The old photos show her casually writing data in a logbook with stacks of lead bricks nearby, or sealing a vacuum chamber with a wrench. ORNL researcher Frances Pleasonton was instrumental in some of the earliest explorations of the properties of the neutron as the X-10 Site was finding its postwar footing as a research lab.

Researchers at Oak Ridge National Laboratory developed an eco-friendly foam insulation for improved building efficiency. Credit: Chad Malone/ORNL, U.S. Dept. of Energy

Scientists at ORNL developed a competitive, eco-friendly alternative made without harmful blowing agents.

Vincente Guiseppe, co-spokesperson of the Majorana Collaboration and a research staff member at ORNL, in front of the Majorana Demonstrator shield on the 4850 Level of SURF. Credit: Nick Hubbard/Sanford Underground Research Facility

For nearly six years, the Majorana Demonstrator quietly listened to the universe. Nearly a mile underground at the Sanford Underground Research Facility, or SURF, in Lead, South Dakota, the experiment collected data that could answer one of the most perplexing questions in physics: Why is the universe filled with something instead of nothing?

Computational systems biologists at ORNL worked with the U.S. Department of Veterans Affairs and other institutions to identify 139 locations across the human genome tied to risk factors for varicose veins, marking a first step in the development of new treatments. Credit: Andy Sproles/ORNL, U.S. Dept. of Energy

As part of a multi-institutional research project, scientists at ORNL leveraged their computational systems biology expertise and the largest, most diverse set of health data to date to explore the genetic basis of varicose veins.