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Media Contacts
![ORNL’s Adam Guss began adapting the SAGE gene editing tool to modify microbes in graduate school. Today, SAGE is rapidly accelerating the design of custom microbes for a variety of applications. Credit: Carlos Jones/ORNL, U.S. Dept. of Energy](/sites/default/files/styles/list_page_thumbnail/public/2023-03/GussPetri_2021-P05223_0.png?h=82f92a78&itok=tqHo8Y9C)
A DNA editing tool adapted by Oak Ridge National Laboratory scientists makes engineering microbes for everything from bioenergy production to plastics recycling easier and faster.
![Computational systems biologists at ORNL worked with the U.S. Department of Veterans Affairs and other institutions to identify 139 locations across the human genome tied to risk factors for varicose veins, marking a first step in the development of new treatments. Credit: Andy Sproles/ORNL, U.S. Dept. of Energy](/sites/default/files/styles/list_page_thumbnail/public/2023-01/vein06_0.jpg?h=d32448e0&itok=ItaGWCo5)
As part of a multi-institutional research project, scientists at ORNL leveraged their computational systems biology expertise and the largest, most diverse set of health data to date to explore the genetic basis of varicose veins.
![Merlin Theodore](/sites/default/files/styles/list_page_thumbnail/public/2023-01/theodore.jpg?h=d1cb525d&itok=9ch50wSj)
Merlin Theodore is one of eight new board members announced by President Biden; she will join the 25-member board for a six-year term.
![A team of ORNL researchers used neutron diffraction experiments to study the 3D-printed ACMZ alloy and observed a phenomenon called “load shuffling” that could inform the design of stronger, better-performing lightweight materials for vehicles. Credit: ORNL, U.S. Dept. of Energy](/sites/default/files/styles/list_page_thumbnail/public/2023-01/loadShuffle01_0_0.png?h=9651c94c&itok=FIdoRoNe)
ORNL researchers have identified a mechanism in a 3D-printed alloy – termed “load shuffling” — that could enable the design of better-performing lightweight materials for vehicles.