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![ORNL’s Brenda Pracheil, left, and Kristine Moody collect water samples at Melton Hill Lake using a sophisticated instrument that collects DNA in the water to determine fish species and number of fish in the water, which could prove useful for monitoring hydropower impacts. Credit: Carlos Jones, ORNL/U.S Dept. of Energy](/sites/default/files/styles/list_page_thumbnail/public/2022-01/2020-P17436_0.jpg?h=c6980913&itok=BXPhSslk)
Researchers at Oak Ridge National Laboratory are using a novel approach in determining environmental impacts to aquatic species near hydropower facilities, potentially leading to smarter facility designs that can support electrical grid reliability.
![A new process developed by Oak Ridge National Laboratory leverages deep learning techniques to study cell movements in a simulated environment, guided by simple physics rules similar to video-game play. Credit: MSKCC and UTK](/sites/default/files/styles/list_page_thumbnail/public/2022-01/Observed%20data%20AI%20story%20tip.jpg?h=8e5dac0a&itok=wrAOsfIs)
Scientists have developed a novel approach to computationally infer previously undetected behaviors within complex biological environments by analyzing live, time-lapsed images that show the positioning of embryonic cells in C. elegans, or roundworms. Their published methods could be used to reveal hidden biological activity.
![ORNL scientists used an electron beam for precision machining of nanoscale materials. Cubes were milled to change their shape and could also be removed from an array. Credit: Kevin Roccapriore/ORNL, U.S. Dept. of Energy](/sites/default/files/styles/list_page_thumbnail/public/2022-01/ORNL_15nm_allmodes_oneper_01.jpg?h=6f770d0b&itok=o5CcrpFN)
Drilling with the beam of an electron microscope, scientists at ORNL precisely machined tiny electrically conductive cubes that can interact with light and organized them in patterned structures that confine and relay light’s electromagnetic signal.
![An ORNL-led team studied the SARS-CoV-2 spike protein in the trimer state, shown here, to pinpoint structural transitions that could be disrupted to destabilize the protein and negate its harmful effects. Credit: Debsindhu Bhowmik/ORNL, U.S. Dept. of Energy](/sites/default/files/styles/list_page_thumbnail/public/2022-01/sars_cov_2_bk.png?h=05c2797f&itok=jQ2D9aTr)
To explore the inner workings of severe acute respiratory syndrome coronavirus 2, or SARS-CoV-2, researchers from ORNL developed a novel technique.
![This protein drives key processes for sulfide use in many microorganisms that produce methane, including Thermosipho melanesiensis. Researchers used supercomputing and deep learning tools to predict its structure, which has eluded experimental methods such as crystallography. Credit: Ada Sedova/ORNL, U.S. Dept. of Energy](/sites/default/files/styles/list_page_thumbnail/public/2022-01/thermosipho_collabfold2_0.jpg?h=3432ff3c&itok=4xhLbjKZ)
A team of scientists led by the Department of Energy’s Oak Ridge National Laboratory and the Georgia Institute of Technology is using supercomputing and revolutionary deep learning tools to predict the structures and roles of thousands of proteins with unknown functions.
![ORNL’s Eva Zarkadoula seeks piezoelectric materials for sensors that can withstand irradiation, which causes cascading collisions that displace atoms and produces defects. Credit: Carlos Jones/ORNL, U.S. Dept. of Energy](/sites/default/files/styles/list_page_thumbnail/public/2022-01/2021-P10023_0.jpg?h=8f9cfe54&itok=6mtG9JEk)
To advance sensor technologies, Oak Ridge National Laboratory researchers studied piezoelectric materials, which convert mechanical stress into electrical energy, to see how they could handle bombardment with energetic neutrons.