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![Brian Fricke, equipment research group lead at ORNL, works with Anthony Gehl at the Building Technologies Research and Integration Center on a new prototype installation. Collaboration with fellow researchers across the building technologies area strengthens his group’s capabilities. Credit: ORNL, U.S. Dept. of Energy](/sites/default/files/styles/list_page_thumbnail/public/2022-01/2021-P09440_0.jpg?h=c6980913&itok=Hrm3cQdU)
When Brian Fricke walks into a supermarket, evidence of his scientific achievement is all around in the refrigerated cases housing the fresh fruits and vegetables. As an Oak Ridge National Laboratory building equipment researcher, Fricke has a long history of making sure that produce is kept fresh in an energy efficient and environmentally sound manner.
![This protein drives key processes for sulfide use in many microorganisms that produce methane, including Thermosipho melanesiensis. Researchers used supercomputing and deep learning tools to predict its structure, which has eluded experimental methods such as crystallography. Credit: Ada Sedova/ORNL, U.S. Dept. of Energy](/sites/default/files/styles/list_page_thumbnail/public/2022-01/thermosipho_collabfold2_0.jpg?h=3432ff3c&itok=4xhLbjKZ)
A team of scientists led by the Department of Energy’s Oak Ridge National Laboratory and the Georgia Institute of Technology is using supercomputing and revolutionary deep learning tools to predict the structures and roles of thousands of proteins with unknown functions.
![ORNL researchers proved that COVID-19 vaccines can be kept ultra-cool for an extended period in a retrofitted commercial storage container, providing a resource for safe delivery to remote locations. Credit: ORNL, U.S. Dept. of Energy](/sites/default/files/styles/list_page_thumbnail/public/2022-01/UnitOnTestSite_0.jpg?h=71976bb4&itok=HEVKqbrK)
Oak Ridge National Laboratory researchers have retrofitted a commercial refrigeration container designed to ensure COVID-19 vaccines remain at ultra-low temperatures during long transport and while locally stored.