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Jack Cahill of ORNL’s Biosciences Division is developing new techniques to view and measure the previously unseen to better understand important chemical processes at play in plant-microbe interactions and in human health. In this photo, Cahill is positioning a rhizosphere-on-a-chip platform for imaging by mass spectrometry. Credit: Carlos Jones/ORNL, U.S. Dept of Energy

John “Jack” Cahill is out to illuminate previously unseen processes with new technology, advancing our understanding of how chemicals interact to influence complex systems whether it’s in the human body or in the world beneath our feet.

ORNL researchers led by Michael Garvin, left, and David Kainer discovered genetic mutations called structural variants and linked them to autism spectrum disorders, demonstrating an approach that could be used to develop better diagnostics and drug therapies. Credit: Carlos Jones/ORNL, U.S. Dept. of Energy

ORNL researchers discovered genetic mutations that underlie autism using a new approach that could lead to better diagnostics and drug therapies.

Matthew Craig’s research at ORNL is focused on how carbon cycles in and out of soils, a process that can have tremendous impact on the Earth’s climate. Credit: Carlos Jones/ORNL, U.S. Dept. of Energy

Matthew Craig grew up eagerly exploring the forest patches and knee-high waterfalls just beyond his backyard in central Illinois’ corn belt. Today, that natural curiosity and the expertise he’s cultivated in biogeochemistry and ecology are focused on how carbon cycles in and out of soils, a process that can have tremendous impact on the Earth’s climate.

ORNL’s Tomás Rush explores the secret lives of fungi and plants for insights into the interactions that determine plant health. Credit: Genevieve Martin/ORNL, U.S. Dept. of Energy

Tomás Rush began studying the mysteries of fungi in fifth grade and spent his college intern days tromping through forests, swamps and agricultural lands searching for signs of fungal plant pathogens causing disease on host plants.

Scientists used genome sequencing and computational biology to tease out the genetic profile of a new moss species, Sphagnum magni, typically found in the southeastern United States. Credit: Blanka Aguero, Duke University

A team from Oak Ridge National Laboratory, Duke University and other institutions studying Sphagnum moss have identified two new species in North America, and they are learning how evolution may affect the species’ role in carbon storage.

Researchers at Oak Ridge National Laboratory probed the chemistry of radium to gain key insights on advancing cancer treatments using radiation therapy. Credit: Adam Malin/ORNL, U.S. Dept. of Energy

Researchers at ORNL explored radium’s chemistry to advance cancer treatments using ionizing radiation.

Researchers used quantum Monte Carlo calculations to accurately render the structure and electronic properties of germanium selenide, a semiconducting nanomaterial. Credit: Paul Kent/ORNL, U.S. Dept. of Energy

A multi-lab research team led by ORNL's Paul Kent is developing a computer application called QMCPACK to enable precise and reliable predictions of the fundamental properties of materials critical in energy research.

Thylakoid

A team of scientists led by Oak Ridge National Laboratory developed a theory that thylakoids, membrane networks key to plant photosynthesis, also function as a defense mechanism to harsh growing conditions, which could aid the development of hardier plants.

Sophie Voisin, an ORNL software engineer, was part of a team that won a 2014 R&D 100 Award for work on Intelligent Software for a Personalized Modeling of Expert Opinions, Decisions and Errors in Visual Examination Tasks. Credit: Jason Richards/ORNL, U.S. Dept. of Energy

Cameras see the world differently than humans. Resolution, equipment, lighting, distance and atmospheric conditions can impact how a person interprets objects on a photo.

Samarthya Bhagia examines a sample of a thermoplastic composite material additively manufactured using poplar wood and polylactic acid. Credit: Carlos Jones/ORNL, U.S. Dept. of Energy

Chemical and environmental engineer Samarthya Bhagia is focused on achieving carbon neutrality and a circular economy by designing new plant-based materials for a range of applications from energy storage devices and sensors to environmentally friendly bioplastics.