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Parans Paranthaman, a researcher in the Chemical Sciences Division at ORNL, coordinated research efforts to study the filter efficiency of the N95 material. His published results represent one of the first studies on polypropylene as it relates to COVID-19. Credit: ORNL/U.S. Dept. of Energy

When COVID-19 was declared a pandemic in March 2020, Oak Ridge National Laboratory’s Parans Paranthaman suddenly found himself working from home like millions of others.

ATOM logo

The Accelerating Therapeutics for Opportunities in Medicine , or ATOM, consortium today announced the U.S. Department of Energy’s Oak Ridge, Argonne and Brookhaven national laboratories are joining the consortium to further develop ATOM’s artificial intelligence, or AI-driven, drug discovery platform.

Targeted alpha therapy can deliver radiation to specific cells, with minimal effect on surrounding, healthy cells. Credit: Michelle Lehman and Jaimee Janiga/ORNL, U.S. Dept. of Energy

A rare isotope in high demand for treating cancer is now more available to pharmaceutical companies developing and testing new drugs.

Data from the ORNL Free Air CO2 Enrichment experiment were combined with observations from more than 100 other FACE sites for this analysis, which revealed new insights about the relationship between plant biomass growth and soil carbon storage. Credit: Jeff Warren/ORNL, U.S. Dept. of Energy

Oak Ridge National Laboratory was among an international team, led by Lawrence Livermore National Laboratory, who synthesized 108 elevated carbon dioxide, or CO2, experiments performed in various ecosystems to find out how much carbon is

Neutron scattering experiments show electric charges, shown in red, blue and grey, in the SARS-CoV-2 main protease site where telaprevir binds to the structure. The experiments provide critical data for the design of small-molecule drugs to treat COVID-19. Credit: Jill Hemman and Michelle Lehman/ORNL, U.S. Dept. of Energy

Scientists have found new, unexpected behaviors when SARS-CoV-2 – the virus that causes COVID-19 – encounters drugs known as inhibitors, which bind to certain components of the virus and block its ability to reproduce.  

Urban climate modeling

Researchers at Oak Ridge National Laboratory have identified a statistical relationship between the growth of cities and the spread of paved surfaces like roads and sidewalks. These impervious surfaces impede the flow of water into the ground, affecting the water cycle and, by extension, the climate.

Technicians John Dyer and T. Dyer use a manipulator arm in a shielded cave in ORNL’s Radiochemical Engineering Development Center to separate concentrated Pm-147 from byproducts generated through the production of Pu-238.

A new method developed at Oak Ridge National Laboratory proves one effort’s trash is another’s valuable isotope. One of the byproducts of the lab’s national plutonium-238 production program is promethium-147, a rare isotope used in nuclear batteries and to measure the thickness of materials.

Ken Andersen

Ken Andersen has been named associate laboratory director for the Neutron Sciences Directorate, or NScD, at the Department of Energy’s Oak Ridge National Laboratory.

The pressure cell uses two gem-quality synthetic opposing diamonds to exert extreme pressures on materials, providing fundamental insights into materials that only neutrons can reveal. Credit: Genevieve Martin/ORNL, U.S. Dept. of Energy

Researchers at Oak Ridge National Laboratory’s Spallation Neutron Source have developed a diamond anvil pressure cell that will enable high-pressure science currently not possible at any other neutron source in the world.

Saplings in an aspen grove recovering from wildfire have more fungal pathogens in their leaves than the original trees. Credit: Chris Schadt/ORNL, U.S. Dept. of Energy

An Oak Ridge National Laboratory research team discovered that aspen saplings emerging after wildfire have less diverse microbiomes and more pathogens in their leaves, providing new insights about how fire affects ecosystem recovery.