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Targeted alpha therapy can deliver radiation to specific cells, with minimal effect on surrounding, healthy cells. Credit: Michelle Lehman and Jaimee Janiga/ORNL, U.S. Dept. of Energy

A rare isotope in high demand for treating cancer is now more available to pharmaceutical companies developing and testing new drugs.

Neutron scattering experiments show electric charges, shown in red, blue and grey, in the SARS-CoV-2 main protease site where telaprevir binds to the structure. The experiments provide critical data for the design of small-molecule drugs to treat COVID-19. Credit: Jill Hemman and Michelle Lehman/ORNL, U.S. Dept. of Energy

Scientists have found new, unexpected behaviors when SARS-CoV-2 – the virus that causes COVID-19 – encounters drugs known as inhibitors, which bind to certain components of the virus and block its ability to reproduce.  

Ken Andersen

Ken Andersen has been named associate laboratory director for the Neutron Sciences Directorate, or NScD, at the Department of Energy’s Oak Ridge National Laboratory.

The pressure cell uses two gem-quality synthetic opposing diamonds to exert extreme pressures on materials, providing fundamental insights into materials that only neutrons can reveal. Credit: Genevieve Martin/ORNL, U.S. Dept. of Energy

Researchers at Oak Ridge National Laboratory’s Spallation Neutron Source have developed a diamond anvil pressure cell that will enable high-pressure science currently not possible at any other neutron source in the world.

Oak Ridge National Laboratory entrance sign

Balendra Sutharshan, deputy associate laboratory director for operational systems at DOE’s Pacific Northwest National Laboratory, has joined ORNL as associate laboratory director for the Isotope Science and Engineering Directorate.

ORNL recognized the small businesses that have made a positive impact on ORNL’s operations at the virtual 2020 Small Business Awards. Credit: ORNL, U.S. Dept. of Energy

Thirty-two Oak Ridge National Laboratory employees were named among teams recognized by former DOE Secretary Dan Brouillette with Secretary’s Honor Awards as he completed his term. Four teams received new awards that reflect DOE responses to the coronavirus pandemic.

ORNL welder Devin Johnson uses a new orbital welder to seal a hollow target in a glovebox in the lab’s Radiochemical Engineering Development Center. The new welder makes a clean seam on the metal target, eliminating the need for hand-finishing afterward. Credit: Carlos Jones/ORNL, U.S. Dept. of Energy

A better way of welding targets for Oak Ridge National Laboratory’s plutonium-238 production has sped up the process and improved consistency and efficiency. This advancement will ultimately benefit the lab’s goal to make enough Pu-238 – the isotope that powers NASA’s deep space missions – to yield 1.5 kilograms of plutonium oxide annually by 2026.

SCGSR Awardee Jacob Zettlemoyer, Indiana University Bloomington, led data analysis and worked with ORNL’s Mike Febbraro on coatings, shown under blue light, to shift argon light to visible wavelengths to boost detection. Credit: Rex Tayloe/Indiana University

The COHERENT particle physics experiment at the Department of Energy’s Oak Ridge National Laboratory has firmly established the existence of a new kind of neutrino interaction.

self-healing elastomers
Researchers at Oak Ridge National Laboratory developed self-healing elastomers that demonstrated unprecedented adhesion strength and the ability to adhere to many surfaces, which could broaden their potential use
An international research team used scanning tunneling microscopy at ORNL to send and receive single molecules across a surface on an atomically precise track. Credit: Michelle Lehman/ORNL, U.S. Dept. of Energy

Oak Ridge National Laboratory’s Center for Nanophase Materials Sciences contributed to a groundbreaking experiment published in Science that tracks the real-time transport of individual molecules.