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Neutron scattering experiments show electric charges, shown in red, blue and grey, in the SARS-CoV-2 main protease site where telaprevir binds to the structure. The experiments provide critical data for the design of small-molecule drugs to treat COVID-19. Credit: Jill Hemman and Michelle Lehman/ORNL, U.S. Dept. of Energy

Scientists have found new, unexpected behaviors when SARS-CoV-2 – the virus that causes COVID-19 – encounters drugs known as inhibitors, which bind to certain components of the virus and block its ability to reproduce.  

Urban climate modeling

Researchers at Oak Ridge National Laboratory have identified a statistical relationship between the growth of cities and the spread of paved surfaces like roads and sidewalks. These impervious surfaces impede the flow of water into the ground, affecting the water cycle and, by extension, the climate.

Saplings in an aspen grove recovering from wildfire have more fungal pathogens in their leaves than the original trees. Credit: Chris Schadt/ORNL, U.S. Dept. of Energy

An Oak Ridge National Laboratory research team discovered that aspen saplings emerging after wildfire have less diverse microbiomes and more pathogens in their leaves, providing new insights about how fire affects ecosystem recovery.

Verónica Melesse Vergara speaks with third and fourth graders at East Side Intermediate School in Brownsville. Credit: ORNL, U.S. Dept. of Energy

Twenty-seven ORNL researchers Zoomed into 11 middle schools across Tennessee during the annual Engineers Week in February. East Tennessee schools throughout Oak Ridge and Roane, Sevier, Blount and Loudon counties participated, with three West Tennessee schools joining in.

The ORNL National Center for Computational Sciences is now home two Hewlett Packard Enterprise, or HPE, Cray EX supercomputers that will provide the U.S. Army and Air Force with global and regional numerical weather model outputs for planning and executing missions worldwide. Credit: Jason Smith/ORNL, U.S. Dept. of Energy and HPE Cray

The U.S. Air Force and Oak Ridge National Laboratory launched a new high-performance weather forecasting computer system that will provide a platform for some of the most advanced weather modeling in the world.

Pella Marion

A new Department of Energy report produced by Oak Ridge National Laboratory details national and international trends in hydropower, including the role waterpower plays in enhancing the flexibility and resilience of the power grid.

Deep-sea hydrothermal vent chimneys on Brother’s Volcano’s northwest caldera wall create a unique environment for microbes. Credit: Anna-Louise Reysenbach, NSF, ROV Jason and 2018 ©Woods Hole Oceanographic Institution

Oak Ridge National Laboratory contributed to an international study that found almost 300 novel types of microbes living near a deep sea volcano. These microbes, which could be used in biotechnology, reveal new insights about their extreme underwater environment.

The TRITON model provides a detailed visualization of the flooding that resulted when Hurricane Harvey stalled over Houston for four days in 2017. Credit: Mario Morales-Hernández/ORNL, U.S. Dept. of Energy

A new tool from Oak Ridge National Laboratory can help planners, emergency responders and scientists visualize how flood waters will spread for any scenario and terrain.