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![Seeing the difference Ac-225 could make to cancer patients made Raina Setzer want to come to ORNL to directly work with the isotope. Credit: Allison Peacock/ORNL, U.S. Dept. of Energy](/sites/default/files/styles/list_page_thumbnail/public/2023-11/rs_0.jpg?h=71976bb4&itok=nFsgqwUT)
Raina Setzer knows the work she does matters. That’s because she’s already seen it from the other side. Setzer, a radiochemical processing technician in Oak Ridge National Laboratory’s Isotope Processing and Manufacturing Division, joined the lab in June 2023.
![Plutonium oxide is loaded onto a truck for shipping. Adam Parkison/ORNL, U.S. Dept. of Energy](/sites/default/files/styles/list_page_thumbnail/public/2023-09/PXL_20230620_120836896_0.jpg?h=2848f5af&itok=Nh31DLuy)
In June, ORNL hit a milestone not seen in more than three decades: producing a production-quality amount of plutonium-238
![Brian Damiano](/sites/default/files/styles/list_page_thumbnail/public/2020-12/2016-P04442.jpg?h=49ab6177&itok=lPIC-H6L)
Brian Damiano, head of the Centrifuge Engineering and Fabrication Section, has been elected fellow of the American Society of Mechanical Engineers.
![asset management](/sites/default/files/styles/list_page_thumbnail/public/2023-05/Picture9.png?h=cf4f3851&itok=rVU02eNT)
East Tennessee occupies a special place in nuclear history. In 1943, the world’s first continuously operating reactor began operating on land that would become ORNL.
![Sandra Davern performs cell based assays to evaluate cell death and DNA damage in response to radiation in order to gain a better understanding of how radioisotope nanoparticles affect the human body.](/sites/default/files/styles/list_page_thumbnail/public/2020-10/2020-P15712.jpg?h=036a71b7&itok=6cpxN4v2)
When Sandra Davern looks to the future, she sees individualized isotopes sent into the body with a specific target: cancer cells.