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The first neutron structure of the SARS-CoV-2 main protease enzyme revealed unexpected electrical charges in the amino acids cysteine (negative) and histidine (positive), providing key data about the virus’s replication. Credit: Jill Hemman/ORNL, U.S. Dept. of Energy

To better understand how the novel coronavirus behaves and how it can be stopped, scientists have completed a three-dimensional map that reveals the location of every atom in an enzyme molecule critical to SARS-CoV-2 reproduction.

William Peter

The Society of Manufacturing Engineers, known as SME, has named William Peter, director of Oak Ridge National Laboratory’s Manufacturing Demonstration Facility in the Energy and Environmental Sciences Directorate, among its 2020 College of SME Fellows.

Researcher Chase Joslin uses Peregrine software to monitor and analyze a component being 3D printed at the Manufacturing Demonstration Facility at ORNL. Credit: Luke Scime/ORNL, U.S. Dept. of Energy.

Oak Ridge National Laboratory researchers have developed artificial intelligence software for powder bed 3D printers that assesses the quality of parts in real time, without the need for expensive characterization equipment.

Andrew Harter, pictured, and fellow ORNL staff members formed Horizon31 to build a set of products and services that provide customized unmanned vehicle control systems. Credit: Carlos Jones/ORNL, U.S. Dept. of Energy

Horizon31, LLC has exclusively licensed a novel communication system that allows users to reliably operate unmanned vehicles such as drones from anywhere in the world using only an internet connection.

Enzyme activity during organophosphate poisoning

Pick your poison. It can be deadly for good reasons such as protecting crops from harmful insects or fighting parasite infection as medicine — or for evil as a weapon for bioterrorism. Or, in extremely diluted amounts, it can be used to enhance beauty.

The Reactive Additive Manufacturing, or RAM, machine for large-scale thermoset printing supports two technologies licensed by MVP and developed in collaboration with ORNL. Credit: Carlos Jones/ORNL, U.S. Dept. of Energy.

ORNL has licensed two additive manufacturing-related technologies that aim to streamline and ramp up production processes to Knoxville-based Magnum Venus Products, Inc., a global manufacturer of fluid movement and product solutions for industrial applications in composites and adhesives.

The CrossVis application includes a parallel coordinates plot (left), a tiled image view (right) and other interactive data views. Credit: Chad Steed/Oak Ridge National Laboratory, U.S. Dept. of Energy

From materials science and earth system modeling to quantum information science and cybersecurity, experts in many fields run simulations and conduct experiments to collect the abundance of data necessary for scientific progress.

The protease protein is both shaped like a heart and functions as one, allowing the virus replicate and spread. Inhibiting the protease would block virus reproduction. Credit: Andrey Kovalevsky/ORNL, U.S. Dept. of Energy

A team of researchers has performed the first room-temperature X-ray measurements on the SARS-CoV-2 main protease — the enzyme that enables the virus to reproduce.

ORNL’s Bianca Haberl and Amy Elliott hold 3D-printed collimators — an invention that has been licensed to ExOne, a leading binder jet 3D printer company. Credit: Genevieve Martin/Oak Ridge National Laboratory, U.S. Dept. of Energy

Oak Ridge National Laboratory has licensed a novel method to 3D print components used in neutron instruments for scientific research to the ExOne Company, a leading maker of binder jet 3D printing technology.

Recent research involving Oak Ridge National Laboratory’s Spallation Neutron Source demonstrates crystal-like heat conduction in a solid-liquid hybrid, AgCrSe2.

Research by an international team led by Duke University and the Department of Energy’s Oak Ridge National Laboratory scientists could speed the way to safer rechargeable batteries for consumer electronics such as laptops and cellphones.