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ORNL scientists developed a method that improves the accuracy of the CRISPR Cas9 gene editing tool used to modify microbes for renewable fuels and chemicals production. This research draws on the lab’s expertise in quantum biology, artificial intelligence and synthetic biology. Credit: Philip Gray/ORNL, U.S. Dept. of Energy

Scientists at ORNL used their expertise in quantum biology, artificial intelligence and bioengineering to improve how CRISPR Cas9 genome editing tools work on organisms like microbes that can be modified to produce renewable fuels and chemicals.

Frontier supercomputer

Innovations in artificial intelligence are rapidly shaping our world, from virtual assistants and chatbots to self-driving cars and automated manufacturing.

Matt Sieger. Credit: Carlos Jones/ORNL

The Oak Ridge Leadership Computing Facility’s Matt Sieger has been named the project director for the OLCF-6 effort. This next OLCF undertaking will plan and build a world-class successor to the OLCF’s still-new exascale system, Frontier.

The Frontier supercomputer at ORNL remains in the number one spot on the May 2023 TOP500 rankings, with an updated high-performance Linpack score of 1.194 exaflops. Engineers at the Oak Ridge Leadership Computing Facility, which houses Frontier and its predecessor Summit, expect that Frontier’s speeds could ultimately top 1.4 exaflops, or 1.4 quintillion calculations per second. Credit: Carlos Jones/ORNL, U.S. Dept. of Energy

With the world’s first exascale supercomputing system now open to full user operations, research teams are harnessing Frontier’s power and speed to tackle some of the most challenging problems in modern science.

Michael Parks

ORNL has named Michael Parks director of the Computer Science and Mathematics Division within ORNL’s Computing and Computational Sciences Directorate. His hiring became effective March 13.

Distinguished Inventors

Six scientists at the Department of Energy’s Oak Ridge National Laboratory were named Battelle Distinguished Inventors, in recognition of obtaining 14 or more patents during their careers at the lab.

Pu-238 pellet drawing

After its long journey to Mars beginning this summer, NASA’s Perseverance rover will be powered across the planet’s surface in part by plutonium produced at the Department of Energy’s Oak Ridge National Laboratory.

Analyses of lung fluid cells from COVID-19 patients conducted on the nation’s fastest supercomputer point to gene expression patterns that may explain the runaway symptoms produced by the body’s response to SARS-CoV-2. Credit: Jason B. Smith/ORNL, U.S. Dept. of Energy

A team led by Dan Jacobson of Oak Ridge National Laboratory used the Summit supercomputer at ORNL to analyze genes from cells in the lung fluid of nine COVID-19 patients compared with 40 control patients.

The protease protein is both shaped like a heart and functions as one, allowing the virus replicate and spread. Inhibiting the protease would block virus reproduction. Credit: Andrey Kovalevsky/ORNL, U.S. Dept. of Energy

A team of researchers has performed the first room-temperature X-ray measurements on the SARS-CoV-2 main protease — the enzyme that enables the virus to reproduce.

Transformational Challenge Reactor Demonstration items

Researchers at the Department of Energy’s Oak Ridge National Laboratory are refining their design of a 3D-printed nuclear reactor core, scaling up the additive manufacturing process necessary to build it, and developing methods