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ORNL researchers led by Michael Garvin, left, and David Kainer discovered genetic mutations called structural variants and linked them to autism spectrum disorders, demonstrating an approach that could be used to develop better diagnostics and drug therapies. Credit: Carlos Jones/ORNL, U.S. Dept. of Energy

ORNL researchers discovered genetic mutations that underlie autism using a new approach that could lead to better diagnostics and drug therapies.

Researchers at ORNL designed a recyclable carbon fiber material to promote low-carbon manufacturing. Credit: Chad Malone/ORNL, U.S. Dept. of Energy

Oak Ridge National Laboratory scientists designed a recyclable polymer for carbon-fiber composites to enable circular manufacturing of parts that boost energy efficiency in automotive, wind power and aerospace applications.

Researchers from ORNL and Argonne National Laboratory will work with Wabtec, a leading manufacturer of freight locomotives, to develop the hardware and control strategies for a single cylinder, dual-fuel engine to demonstrate the viability of using alternative fuels for locomotives. The team’s goal is to reduce carbon emissions from the roughly 25,000 locomotives already in use in North America. Credit: ORNL, U.S. Dept. of Energy

As the United States shifts away from fossil-fuel-burning cars and trucks, scientists at the Department of Energy’s Oak Ridge and Argonne national laboratories are exploring options for another form of transportation: trains. The research focuses on zero-carbon hydrogen and other low-carbon fuels as viable alternatives to diesel for the rail industry.

This image from Sept. 30, 2022, shows how the Federal Emergency Management Agency used ORNL's USA Structures data along with new satellite images to identify structures that were destroyed in Lee County, Florida, during Hurricane Ian. Credit: ORNL, U.S. Dept. of Energy

Over the past seven years, researchers in ORNL’s Geospatial Science and Human Security Division have mapped and characterized all structures within the United States and its territories to aid FEMA in its response to disasters. This dataset provides a consistent, nationwide accounting of the buildings where people reside and work.

Susan Hubbard, ORNL’s deputy for science and technology, and Ricardo Marc-Antoni Duncanson, founder of Marc-Antoni Racing, celebrated the company's licensing of ORNL-developed technologies during an event on Oct. 17. Credit: Carlos Jones/ORNL, U.S. Dept. of Energy

Marc-Antoni Racing has licensed a collection of patented energy storage technologies developed at ORNL. The technologies focus on components that enable fast-charging, energy-dense batteries for electric and hybrid vehicles and grid storage.

Paul Brackman loads 3D-printed metal samples into a tower for examination using an X-ray CT scan in DOE’s Manufacturing Demonstration Facility at ORNL. Credit: Brittany Cramer/ORNL, U.S. Dept. of Energy

A new deep-learning framework developed at ORNL is speeding up the process of inspecting additively manufactured metal parts using X-ray computed tomography, or CT, while increasing the accuracy of the results. The reduced costs for time, labor, maintenance and energy are expected to accelerate expansion of additive manufacturing, or 3D printing.

ORNL’s Tomás Rush explores the secret lives of fungi and plants for insights into the interactions that determine plant health. Credit: Genevieve Martin/ORNL, U.S. Dept. of Energy

Tomás Rush began studying the mysteries of fungi in fifth grade and spent his college intern days tromping through forests, swamps and agricultural lands searching for signs of fungal plant pathogens causing disease on host plants.

A simulation of the planet from the DOE Energy Exascale Earth System Model, one of the large-scale models incorporated in the Earth System Grid Federation led by DOE’s Oak Ridge, Argonne and Lawrence Livermore national laboratories. Credit: LLNL, U.S. Dept. of Energy

The Earth System Grid Federation, a multi-agency initiative that gathers and distributes data for top-tier projections of the Earth’s climate, is preparing a series of upgrades.

A new online tool developed by ORNL researchers, VERIFI, provides an easy to use dashboard for plant managers to track carbon emissions produced by industrial processes. The tool also monitors energy usage and produces trend reports. Credit: ORNL, U.S. Dept. of Energy

Researchers at ORNL have developed an online tool that offers industrial plants an easier way to track and download information about their energy footprint and carbon emissions.

Shown here is the structure of the NEMO protein. A team from ORNL conducted extensive molecular dynamics work on Summit by using both quantum mechanics and machine-learning methods to look at the binding affinity of NEMO and 3CLpro in humans and other species and to consider the structural models derived from the sequences of other coronaviruses. Image courtesy Nature Communications, Dan Jacobson/ORNL.

A new paper published in Nature Communications adds further evidence to the bradykinin storm theory of COVID-19’s viral pathogenesis — a theory that was posited two years ago by a team of researchers at the Department of Energy’s Oak Ridge National Laboratory.