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The hCA II active site is flanked by hydrophilic (violet) and hydrophobic (green) binding pockets that can be used to design specific drugs targeting cancer-associated hCAs. Five clinical drugs are shown superimposed in the hCA II active site
New insights from neutron analysis of glaucoma drugs and their enzyme target may help scientists design drugs that more effectively target aggressive cancers. A team of researchers led by the Department of Energy’s Oak Ridge National Laboratory used neutro...
ORNL and EPRI built an enclosed welding system in a hot cell of ORNL’s Radiochemical Engineering Development Center. C. Scott White (ORNL) performs operations with remotely controlled manipulators and cameras.

Scientists of the Department of Energy’s Light Water Reactor Sustainability Program (LWRS) and partners from the Electric Power Research Institute (EPRI) have conducted the first weld tests to repair highly irradiated materials at DOE’s Oak Ridge National Laboratory.

Oak Ridge National Laboratory researcher Halil Tekinalp combines silanes and polylactic acid to create supertough renewable plastic.

A novel method developed at Oak Ridge National Laboratory creates supertough renewable plastic with improved manufacturability. Working with polylactic acid, a biobased plastic often used in packaging, textiles, biomedical implants and 3D printing, the research team added tiny amo...

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A team led by the Department of Energy’s Oak Ridge National Laboratory has uncovered how certain soil microbes cope in a phosphorus-poor environment to survive in a tropical ecosystem. Their novel approach could be applied in other ecosystems to study various nutrient limitations and inform agriculture and terrestrial biosphere modeling.
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A new process to identify certain microbes in women could be used to diagnose endometriosis without invasive surgery, even before symptoms start. A collaborative research team including Oak Ridge National Laboratory analyzed bacteria from a small sample of premenopausal women undergoing laparoscopic surgery for suspected endometriosis.
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To improve models for drilling, hydraulic fracturing and underground storage of carbon dioxide, Oak Ridge National Laboratory scientists used neutrons to understand how water flows through fractured rock.
California charging EV station map

Officials responsible for anticipating the demand for electric vehicle charging stations could get help through a sophisticated new method developed at Oak Ridge National Laboratory. The method considers electric vehicle volume and the random timing of vehicles arriving at cha...

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A novel approach for studying magnetic behavior in a material called alpha-ruthenium trichloride may have implications for quantum computing. By suppressing the material’s magnetic order, scientists from Oak Ridge National Laboratory and the University of Tennessee observed be...