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The hCA II active site is flanked by hydrophilic (violet) and hydrophobic (green) binding pockets that can be used to design specific drugs targeting cancer-associated hCAs. Five clinical drugs are shown superimposed in the hCA II active site
New insights from neutron analysis of glaucoma drugs and their enzyme target may help scientists design drugs that more effectively target aggressive cancers. A team of researchers led by the Department of Energy’s Oak Ridge National Laboratory used neutro...
ORNL and EPRI built an enclosed welding system in a hot cell of ORNL’s Radiochemical Engineering Development Center. C. Scott White (ORNL) performs operations with remotely controlled manipulators and cameras.

Scientists of the Department of Energy’s Light Water Reactor Sustainability Program (LWRS) and partners from the Electric Power Research Institute (EPRI) have conducted the first weld tests to repair highly irradiated materials at DOE’s Oak Ridge National Laboratory.

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To improve models for drilling, hydraulic fracturing and underground storage of carbon dioxide, Oak Ridge National Laboratory scientists used neutrons to understand how water flows through fractured rock.
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A novel approach for studying magnetic behavior in a material called alpha-ruthenium trichloride may have implications for quantum computing. By suppressing the material’s magnetic order, scientists from Oak Ridge National Laboratory and the University of Tennessee observed be...