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While studying the genes in poplar trees that control callus formation, scientists at Oak Ridge National Laboratory have uncovered genetic networks at the root of tumor formation in several human cancers.

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Working backwards has moved Josh Michener’s research far forward as he uses evolution and genetics to engineer microbes for better conversion of plants into biofuels and biochemicals. In his work for the BioEnergy Science Center at ORNL, for instance, “we’ve gotten good at engineering microbes th...