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Molecular dynamics simulations of the Fs-peptide revealed the presence of at least eight distinct intermediate stages during the process of protein folding. The image depicts a fully folded helix (1), various transitional forms (2–8), and one misfolded state (9). By studying these protein folding pathways, scientists hope to identify underlying factors that affect human health.

Using artificial neural networks designed to emulate the inner workings of the human brain, deep-learning algorithms deftly peruse and analyze large quantities of data. Applying this technique to science problems can help unearth historically elusive solutions.

(From left) ORNL Associate Laboratory Director for Computing and Computational Sciences Jeff Nichols; ORNL Health Data Sciences Institute Director Gina Tourassi; DOE Deputy Under Secretary for Science Thomas Cubbage; ORNL Task Lead for Biostatistics Blair Christian; and ORNL Research Scientist Ioana Danciu were invited to the White House to showcase an ORNL-developed digital tool aimed at better matching cancer patients with clinical trials.

OAK RIDGE, Tenn., March 4, 2019—A team of researchers from the Department of Energy’s Oak Ridge National Laboratory Health Data Sciences Institute have harnessed the power of artificial intelligence to better match cancer patients with clinical trials.

The EPB Control Center monitors the company’s assets such as substations and buildings.

OAK RIDGE, Tenn., Feb. 12, 2019—A team of researchers from the Department of Energy’s Oak Ridge and Los Alamos National Laboratories has partnered with EPB, a Chattanooga utility and telecommunications company, to demonstrate the effectiveness of metro-scale quantum key distribution (QKD).

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OAK RIDGE, Tenn., Jan. 31, 2019—A new electron microscopy technique that detects the subtle changes in the weight of proteins at the nanoscale—while keeping the sample intact—could open a new pathway for deeper, more comprehensive studies of the basic building blocks of life. 

The interior of the Massachusetts Institute of Technology’s (MIT’s) Alcator C-Mod tokamak. A team led by Princeton Plasma Physics Laboratory’s C.S. Chang recently used the Titan supercomputer

The same fusion reactions that power the sun also occur inside a tokamak, a device that uses magnetic fields to confine and control plasmas of 100-plus million degrees. Under extreme temperatures and pressure, hydrogen atoms can fuse together, creating new helium atoms and simulta...

Arjun Shankar

The field of “Big Data” has exploded in the blink of an eye, growing exponentially into almost every branch of science in just a few decades. Sectors such as energy, manufacturing, healthcare and many others depend on scalable data processing and analysis for continued in...

Scientists will use ORNL’s computing resources such as the Titan supercomputer to develop deep learning solutions for data analysis. Credit: Jason Richards/Oak Ridge National Laboratory, U.S. Dept. of Energy.

A team of researchers from Oak Ridge National Laboratory has been awarded nearly $2 million over three years from the Department of Energy to explore the potential of machine learning in revolutionizing scientific data analysis. The Advances in Machine Learning to Improve Scient...

Methanotroph_OB3b_cells

A team led by the Department of Energy’s Oak Ridge National Laboratory has identified a novel microbial process that can break down toxic methylmercury in the environment, a fundamental scientific discovery that could potentially reduce mercury toxicity levels and sup...

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Virginia-based Lenvio Inc. has exclusively licensed a cyber security technology from the Department of Energy’s Oak Ridge National Laboratory that can quickly detect malicious behavior in software not previously identified as a threat.

The Transforming Additive Manufacturing through Exascale Simulation project (ExaAM) is building a new multi-physics modeling and simulation platform for 3D printing of metals

Oak Ridge National Laboratory experts are playing leading roles in the recently established Department of Energy’s (DOE’s) Exascale Computing Project (ECP), a multi-lab initiative responsible for developing the strategy, aligning the resources, and conducting the R&D necessary to achieve the nation’s imperative of delivering exascale computing by 2021.