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![ORNL scientists developed a method that improves the accuracy of the CRISPR Cas9 gene editing tool used to modify microbes for renewable fuels and chemicals production. This research draws on the lab’s expertise in quantum biology, artificial intelligence and synthetic biology. Credit: Philip Gray/ORNL, U.S. Dept. of Energy](/sites/default/files/styles/list_page_thumbnail/public/2023-11/CRISPR%20Quantum%20AI_2_23-G07105-DOE-BER-BESSD-comms-graphic-pcg_2.jpg?h=847b7ff0&itok=WD2dBsAC)
Scientists at ORNL used their expertise in quantum biology, artificial intelligence and bioengineering to improve how CRISPR Cas9 genome editing tools work on organisms like microbes that can be modified to produce renewable fuels and chemicals.
![Frontier supercomputer](/sites/default/files/styles/list_page_thumbnail/public/2023-06/Frontier-logos_0.jpg?h=c6980913&itok=yuF5A0wj)
Innovations in artificial intelligence are rapidly shaping our world, from virtual assistants and chatbots to self-driving cars and automated manufacturing.
![Ashley Barker. Credit: Carlos Jones/ORNL](/sites/default/files/styles/list_page_thumbnail/public/2023-05/2022-P14022.jpg?h=c6980913&itok=Su1w1TDa)
At the National Center for Computational Sciences, Ashley Barker enjoys one of the least complicated–sounding job titles at ORNL: section head of operations. But within that seemingly ordinary designation lurks a multitude of demanding roles as she oversees the complete user experience for NCCS computer systems.
![Matt Sieger. Credit: Carlos Jones/ORNL](/sites/default/files/styles/list_page_thumbnail/public/2023-05/2022-P00437_0.jpg?h=c6980913&itok=bGz_GUB0)
The Oak Ridge Leadership Computing Facility’s Matt Sieger has been named the project director for the OLCF-6 effort. This next OLCF undertaking will plan and build a world-class successor to the OLCF’s still-new exascale system, Frontier.
![The Frontier supercomputer at ORNL remains in the number one spot on the May 2023 TOP500 rankings, with an updated high-performance Linpack score of 1.194 exaflops. Engineers at the Oak Ridge Leadership Computing Facility, which houses Frontier and its predecessor Summit, expect that Frontier’s speeds could ultimately top 1.4 exaflops, or 1.4 quintillion calculations per second. Credit: Carlos Jones/ORNL, U.S. Dept. of Energy](/sites/default/files/styles/list_page_thumbnail/public/2023-05/2022-P07496_0.jpg?h=c6980913&itok=lkvzQLQ6)
With the world’s first exascale supercomputing system now open to full user operations, research teams are harnessing Frontier’s power and speed to tackle some of the most challenging problems in modern science.
![An AI-generated image representing atoms and artificial neural networks. Credit: Maxim Ziatdinov, ORNL](/sites/default/files/styles/list_page_thumbnail/public/2023-04/atoms3.jpg?h=ab622562&itok=dNMzrFw8)
Researchers at ORNL have developed a machine-learning inspired software package that provides end-to-end image analysis of electron and scanning probe microscopy images.
![Michael Parks](/sites/default/files/styles/list_page_thumbnail/public/2023-04/parks.jpg?h=e55356b9&itok=ziNn868K)
ORNL has named Michael Parks director of the Computer Science and Mathematics Division within ORNL’s Computing and Computational Sciences Directorate. His hiring became effective March 13.
![Distinguished Inventors](/sites/default/files/styles/list_page_thumbnail/public/2020-12/inventors.jpg?h=4631f1c1&itok=xhAGY0kv)
Six scientists at the Department of Energy’s Oak Ridge National Laboratory were named Battelle Distinguished Inventors, in recognition of obtaining 14 or more patents during their careers at the lab.
![Six ORNL scientists have been elected as fellows to the American Association for the Advancement of Science, or AAAS. Credit: ORNL, U.S. Dept. of Energy](/sites/default/files/styles/list_page_thumbnail/public/2020-11/AAASfellows.jpg?h=d761c044&itok=opKRkA17)
Six ORNL scientists have been elected as fellows to the American Association for the Advancement of Science, or AAAS.
![ORNL assisted in investigating proteins called porins, one shown in red, which are found in the protective outer membrane of certain disease-causing bacteria and tether the membrane to the cell wall. Credit: Hyea (Sunny) Hwang/Georgia Tech and ORNL, U.S. Dept. of Energy](/sites/default/files/styles/list_page_thumbnail/public/2020-11/Biology-gram-negative_0.jpg?h=ced0ee1c&itok=mTOudglI)
Scientists from Oak Ridge National Laboratory used high-performance computing to create protein models that helped reveal how the outer membrane is tethered to the cell membrane in certain bacteria.