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ORNL researchers led by Michael Garvin, left, and David Kainer discovered genetic mutations called structural variants and linked them to autism spectrum disorders, demonstrating an approach that could be used to develop better diagnostics and drug therapies. Credit: Carlos Jones/ORNL, U.S. Dept. of Energy

ORNL researchers discovered genetic mutations that underlie autism using a new approach that could lead to better diagnostics and drug therapies.

Researchers used quantum Monte Carlo calculations to accurately render the structure and electronic properties of germanium selenide, a semiconducting nanomaterial. Credit: Paul Kent/ORNL, U.S. Dept. of Energy

A multi-lab research team led by ORNL's Paul Kent is developing a computer application called QMCPACK to enable precise and reliable predictions of the fundamental properties of materials critical in energy research.

Oak Ridge National Laboratory researchers developed an invertible neural network, a type of artificial intelligence that mimics the human brain, to improve accuracy in climate-change models and predictions. Credit: Getty Images

Oak Ridge National Laboratory researchers developed an invertible neural network, a type of artificial intelligence that mimics the human brain, to improve accuracy in climate-change models and predictions.

Genetic analysis revealed connections between inflammatory activity and development of atomic dermatitis, according to researchers from the UPenn School of Medicine, the Perelman School of Medicine, and Oak Ridge National Laboratory. Credit: Kang Ko/UPenn

University of Pennsylvania researchers called on computational systems biology expertise at Oak Ridge National Laboratory to analyze large datasets of single-cell RNA sequencing from skin samples afflicted with atopic dermatitis.

ORNL researchers worked with partners at the Colorado School of Mines and Baylor University to develop a new process optimization and control method for a closed-circuit reverse osmosis desalination system. The work is intended to support fully automated, decentralized water treatment plants. Credit: Andrew Sproles/ORNL, U.S. Dept. of Energy

Oak Ridge National Laboratory scientists worked with the Colorado School of Mines and Baylor University to develop and test control methods for autonomous water treatment plants that use less energy and generate less waste.

As hurricanes formed in the Gulf Coast, ORNL activated a computing technique to quickly gather building structure data from Texas’ coastal counties. Credit: Mark Tuttle/Oak Ridge National Laboratory, U.S. Dept. of Energy

Geospatial scientists at Oak Ridge National Laboratory have developed a novel method to quickly gather building structure datasets that support emergency response teams assessing properties damaged by Hurricanes Harvey and Irma. By coupling deep learning with high-performance comp...

ORNL’s Frank Combs and Michael Starr of the U.S. Armed Forces (driver) work in ORNL’s Vehicle Security Laboratory to evaluate a prototype device that can detect network intrusions in all modern vehicles. Credit: Carlos Jones/ORNL, U.S. Dept. of Energy

A new Oak Ridge National Laboratory-developed method promises to protect connected and autonomous vehicles from possible network intrusion. Researchers built a prototype plug-in device designed to alert drivers of vehicle cyberattacks. The prototype is coded to learn regular timing...