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Neutron scattering experiments show electric charges, shown in red, blue and grey, in the SARS-CoV-2 main protease site where telaprevir binds to the structure. The experiments provide critical data for the design of small-molecule drugs to treat COVID-19. Credit: Jill Hemman and Michelle Lehman/ORNL, U.S. Dept. of Energy

Scientists have found new, unexpected behaviors when SARS-CoV-2 – the virus that causes COVID-19 – encounters drugs known as inhibitors, which bind to certain components of the virus and block its ability to reproduce.  

Ken Andersen

Ken Andersen has been named associate laboratory director for the Neutron Sciences Directorate, or NScD, at the Department of Energy’s Oak Ridge National Laboratory.

The pressure cell uses two gem-quality synthetic opposing diamonds to exert extreme pressures on materials, providing fundamental insights into materials that only neutrons can reveal. Credit: Genevieve Martin/ORNL, U.S. Dept. of Energy

Researchers at Oak Ridge National Laboratory’s Spallation Neutron Source have developed a diamond anvil pressure cell that will enable high-pressure science currently not possible at any other neutron source in the world.

Martin Wissink of ORNL’s Buildings and Transportation Science Division applies neutrons and other diagnostic tools at Oak Ridge National Laboratory in pursuit of cleaner, sustainable and more flexible transportation technologies. Credit: Genevieve Martin/ORNL, U.S. Dept of Energy

For a researcher who started out in mechanical engineering with a focus on engine combustion, Martin Wissink has learned a lot about neutrons on the job

Small, 3D-printed neutron collimators, designed by ORNL’s Jamie Molaison, yield reduced costs and manufacturing times and could enable new types of experiments. Credit: Genevieve Martin/ORNL, U.S. Dept. of Energy

The ExOne Company, the global leader in industrial sand and metal 3D printers using binder jetting technology, announced it has reached a commercial license agreement with Oak Ridge National Laboratory to 3D print parts in aluminum-infiltrated boron carbide.

SCGSR Awardee Jacob Zettlemoyer, Indiana University Bloomington, led data analysis and worked with ORNL’s Mike Febbraro on coatings, shown under blue light, to shift argon light to visible wavelengths to boost detection. Credit: Rex Tayloe/Indiana University

The COHERENT particle physics experiment at the Department of Energy’s Oak Ridge National Laboratory has firmly established the existence of a new kind of neutrino interaction.

Eugene Mamontov and the BASIS beam line at the Spallation Neutron Source at ORNL. Photo credit: Jason Richards, ORNL.
Eugene Mamontov’s background in both basic and applied science has made him a valued partner for scientists who come to the Spallation Neutron Source at ORNL in search of a better understanding of the water dynamics in their research—projects as diverse as studying plant cellulos...
Chlorite dismutase - Journal cover art reprinted with permission from ACS Catalysis, vol. 7, issue 11, November 3, 2017. Further permissions related to the material excerpted should be directed to the ACS.

A new study sheds light on a unique enzyme that could provide an eco-friendly treatment for chlorite-contaminated water supplies and improve water quality worldwide. An international team of researchers led by Christian Obinger from the University of Vienna used neutron analys...

Neutrons probed two mechanisms proposed to explain what happens when hydrogen gas flows over a cerium oxide (CeO2) catalyst that has been heated in an experimental chamber to different temperatures to change its oxidation state. The first mechanism sugges
Having the right tool for the job enabled scientists at the Department of Energy’s Oak Ridge National Laboratory and their collaborators to discover that a workhorse catalyst of vehicle exhaust systems—an “oxygen sponge” that can soak up oxygen from air and store it for later use in oxidation reactions—may also be a “hydrogen sponge.”
Bacteria containing enzymes called beta-lactamases, illustrated by the light blue cluster, break down antibiotics and allow bacterial infections to develop and spread through human cells (orange). A team from ORNL’s Neutron Sciences Directorate is using n
The discovery of penicillin almost 90 years ago ushered in the age of modern antibiotics, but the growth of antibiotic resistance means bacterial infections like pneumonia and tuberculosis are becoming more difficult to treat.