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Ashleigh Kimberlin and Mikayla Molnar achieve success with a gas-trapping apparatus for Ac-225 production. Credit: ORNL, U.S. Dept. of Energy

In experiment after experiment, the synthetic radioisotope actinium-225 has shown promise for targeting and attacking certain types of cancer cells.

Initially, Kevin Gaddis’s adapted HPIC will be used only for the fourth of six separations in  actinium-225 processing, but he hopes it will later be used for other separations — and other isotopes. Credit: Carlos Jones/ORNL, U.S. Dept. of Energy

An Oak Ridge National Laboratory researcher has invented a version of an isotope-separating device that can withstand extreme environments, including radiation and chemical solvents.

Targeted alpha therapy can deliver radiation to specific cells, with minimal effect on surrounding, healthy cells. Credit: Michelle Lehman and Jaimee Janiga/ORNL, U.S. Dept. of Energy

A rare isotope in high demand for treating cancer is now more available to pharmaceutical companies developing and testing new drugs.

Oak Ridge National Laboratory entrance sign

Balendra Sutharshan, deputy associate laboratory director for operational systems at DOE’s Pacific Northwest National Laboratory, has joined ORNL as associate laboratory director for the Isotope Science and Engineering Directorate.

ORNL welder Devin Johnson uses a new orbital welder to seal a hollow target in a glovebox in the lab’s Radiochemical Engineering Development Center. The new welder makes a clean seam on the metal target, eliminating the need for hand-finishing afterward. Credit: Carlos Jones/ORNL, U.S. Dept. of Energy

A better way of welding targets for Oak Ridge National Laboratory’s plutonium-238 production has sped up the process and improved consistency and efficiency. This advancement will ultimately benefit the lab’s goal to make enough Pu-238 – the isotope that powers NASA’s deep space missions – to yield 1.5 kilograms of plutonium oxide annually by 2026.