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Molecular dynamics simulations of the Fs-peptide revealed the presence of at least eight distinct intermediate stages during the process of protein folding. The image depicts a fully folded helix (1), various transitional forms (2–8), and one misfolded state (9). By studying these protein folding pathways, scientists hope to identify underlying factors that affect human health.

Using artificial neural networks designed to emulate the inner workings of the human brain, deep-learning algorithms deftly peruse and analyze large quantities of data. Applying this technique to science problems can help unearth historically elusive solutions.

ORNL’s Manjunath Gorentla Venkata helped develop a new approach to analyze thousands of genetic samples by connecting powerful computing resources.

Computing experts at the Department of Energy’s Oak Ridge National Laboratory collaborated with a team of university researchers and software companies to develop a novel hybrid computational strategy to efficiently discover genetic variants