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When an electron beam drills holes in heated graphene, single-atom vacancies, shown in purple, diffuse until they join with other vacancies to form stationary structures and chains, shown in blue. Credit: Ondrej Dyck/ORNL, U.S. Dept. of Energy

Oak Ridge National Laboratory researchers serendipitously discovered when they automated the beam of an electron microscope to precisely drill holes in the atomically thin lattice of graphene, the drilled holes closed up.

Jack Cahill of ORNL’s Biosciences Division is developing new techniques to view and measure the previously unseen to better understand important chemical processes at play in plant-microbe interactions and in human health. In this photo, Cahill is positioning a rhizosphere-on-a-chip platform for imaging by mass spectrometry. Credit: Carlos Jones/ORNL, U.S. Dept of Energy

John “Jack” Cahill is out to illuminate previously unseen processes with new technology, advancing our understanding of how chemicals interact to influence complex systems whether it’s in the human body or in the world beneath our feet.

ORNL researchers led by Michael Garvin, left, and David Kainer discovered genetic mutations called structural variants and linked them to autism spectrum disorders, demonstrating an approach that could be used to develop better diagnostics and drug therapies. Credit: Carlos Jones/ORNL, U.S. Dept. of Energy

ORNL researchers discovered genetic mutations that underlie autism using a new approach that could lead to better diagnostics and drug therapies.

Researchers at Oak Ridge National Laboratory probed the chemistry of radium to gain key insights on advancing cancer treatments using radiation therapy. Credit: Adam Malin/ORNL, U.S. Dept. of Energy

Researchers at ORNL explored radium’s chemistry to advance cancer treatments using ionizing radiation.

Researchers used quantum Monte Carlo calculations to accurately render the structure and electronic properties of germanium selenide, a semiconducting nanomaterial. Credit: Paul Kent/ORNL, U.S. Dept. of Energy

A multi-lab research team led by ORNL's Paul Kent is developing a computer application called QMCPACK to enable precise and reliable predictions of the fundamental properties of materials critical in energy research.

ORNL physicist Libby Johnson demonstrated a new control panel at ORNL’s Bulk Shielding Facility in 1957. Among the first females to operate a nuclear reactor, Johnson blazed trails for women. Credit: ORNL, U.S. Dept. of Energy

Oak Ridge National Laboratory physicist Elizabeth “Libby” Johnson (1921-1996), one of the world’s first nuclear reactor operators, standardized the field of criticality safety with peers from ORNL and Los Alamos National Laboratory.

Sophie Voisin, an ORNL software engineer, was part of a team that won a 2014 R&D 100 Award for work on Intelligent Software for a Personalized Modeling of Expert Opinions, Decisions and Errors in Visual Examination Tasks. Credit: Jason Richards/ORNL, U.S. Dept. of Energy

Cameras see the world differently than humans. Resolution, equipment, lighting, distance and atmospheric conditions can impact how a person interprets objects on a photo.

Samarthya Bhagia examines a sample of a thermoplastic composite material additively manufactured using poplar wood and polylactic acid. Credit: Carlos Jones/ORNL, U.S. Dept. of Energy

Chemical and environmental engineer Samarthya Bhagia is focused on achieving carbon neutrality and a circular economy by designing new plant-based materials for a range of applications from energy storage devices and sensors to environmentally friendly bioplastics.

ORNL identity science researcher Nell Barber works on a facial recognition camera. Credit: Genevieve Martin/ORNL, U.S. Dept. of Energy

Though Nell Barber wasn’t sure what her future held after graduating with a bachelor’s degree in psychology, she now uses her interest in human behavior to design systems that leverage machine learning algorithms to identify faces in a crowd.

Oak Ridge National Laboratory researchers developed an invertible neural network, a type of artificial intelligence that mimics the human brain, to improve accuracy in climate-change models and predictions. Credit: Getty Images

Oak Ridge National Laboratory researchers developed an invertible neural network, a type of artificial intelligence that mimics the human brain, to improve accuracy in climate-change models and predictions.