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Media Contacts
![An organic solvent and water separate and form nanoclusters on the hydrophobic and hydrophilic sections of plant material, driving the efficient deconstruction of biomass. Credit: Michelle Lehman/ORNL, U.S. Dept. of Energy](/sites/default/files/styles/list_page_thumbnail/public/2020-11/dark_image_small.png?h=2e111cc1&itok=drKqW05b)
Experiments led by researchers at ORNL have determined that several hepatitis C drugs can inhibit the SARS-CoV-2 main protease, a crucial protein enzyme that enables the novel coronavirus to reproduce.
![The first neutron structure of the SARS-CoV-2 main protease enzyme revealed unexpected electrical charges in the amino acids cysteine (negative) and histidine (positive), providing key data about the virus’s replication. Credit: Jill Hemman/ORNL, U.S. Dept. of Energy](/sites/default/files/styles/list_page_thumbnail/public/2020-10/20-G01620_Protease_PR_proof2_0.jpg?h=3e3883a3&itok=XB_ZEDFQ)
To better understand how the novel coronavirus behaves and how it can be stopped, scientists have completed a three-dimensional map that reveals the location of every atom in an enzyme molecule critical to SARS-CoV-2 reproduction.
![A selfie from the Curiosity rover as it explores the surface of Mars. Like many spacecraft, Curiosity uses a radioisotope power system to help fuel its mission. Credit: NASA/JPL-Caltech/MSSS](/sites/default/files/styles/list_page_thumbnail/public/2020-09/Curiousity_1.jpg?h=86a9dded&itok=Jo0vD321)
Radioactive isotopes power some of NASA’s best-known spacecraft. But predicting how radiation emitted from these isotopes might affect nearby materials is tricky
![This photo shows the interior of the vessel of the General Atomics DIII-D National Fusion Facility in San Diego, where ORNL researchers are testing the suitability of tungsten to armor the inside of a fusion device. Credit: General Atomics](/sites/default/files/styles/list_page_thumbnail/public/2020-08/X2001140_Tungsten_DIIID_GeneralAtomics_Bumpus_jnj_0.jpg?h=fa422108&itok=9R1Nn6B_)
The inside of future nuclear fusion energy reactors will be among the harshest environments ever produced on Earth. What’s strong enough to protect the inside of a fusion reactor from plasma-produced heat fluxes akin to space shuttles reentering Earth’s atmosphere?
![3D-printed 316L steel has been irradiated along with traditionally wrought steel samples. Researchers are comparing how they perform at various temperatures and varying doses of radiation. Credit: Jaimee Janiga/ORNL](/sites/default/files/styles/list_page_thumbnail/public/2020-08/X2001337_TCR_IrradiatedMaterials_Bumpus_jnj-04.jpg?h=e3a8e2b5&itok=pXslTCBN)
It’s a new type of nuclear reactor core. And the materials that will make it up are novel — products of Oak Ridge National Laboratory’s advanced materials and manufacturing technologies.
![VERA’s tools allow a virtual window inside the reactor core, down to a molecular level.](/sites/default/files/styles/list_page_thumbnail/public/2020-08/Godfrey_2d_pin_power.png?h=507248e9&itok=SIcNrXUE)
As CASL ends and transitions to VERA Users Group, ORNL looks at the history of the program and its impact on the nuclear industry.
![Pu-238 pellet drawing](/sites/default/files/styles/list_page_thumbnail/public/2020-07/Plutonium_Illustration_Blur.png?h=b6236d98&itok=wvSAbP64)
After its long journey to Mars beginning this summer, NASA’s Perseverance rover will be powered across the planet’s surface in part by plutonium produced at the Department of Energy’s Oak Ridge National Laboratory.
![ORNL’s Drew Elliott served as a major collaborator in upgrading the Princeton Plasma Physics Laboratory’s Lithium Tokamak Experiment-Beta. Credit: Robert Kaita, Princeton Plasma Physics Laboratory](/sites/default/files/styles/list_page_thumbnail/public/2020-07/Drew%20Elliot_1.jpg?h=8f8cd18c&itok=U-2mXJIG)
Lithium, the silvery metal that powers smart phones and helps treat bipolar disorders, could also play a significant role in the worldwide effort to harvest on Earth the safe, clean and virtually limitless fusion energy that powers the sun and stars.
![An organic solvent and water separate and form nanoclusters on the hydrophobic and hydrophilic sections of plant material, driving the efficient deconstruction of biomass. Credit: Michelle Lehman/ORNL, U.S. Dept. of Energy](/sites/default/files/styles/list_page_thumbnail/public/2020-07/THF_high_res.gif?h=5a472534&itok=5peedFnF)
Scientists at ORNL used neutron scattering and supercomputing to better understand how an organic solvent and water work together to break down plant biomass, creating a pathway to significantly improve the production of renewable
![The protease protein is both shaped like a heart and functions as one, allowing the virus replicate and spread. Inhibiting the protease would block virus reproduction. Credit: Andrey Kovalevsky/ORNL, U.S. Dept. of Energy](/sites/default/files/styles/list_page_thumbnail/public/2020-06/protease_dimer_3_1.png?h=aa51a450&itok=sJY7AB8d)
A team of researchers has performed the first room-temperature X-ray measurements on the SARS-CoV-2 main protease — the enzyme that enables the virus to reproduce.