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![Computational biophysicist Ada Sedova is using experiments and high-performance computing to explore the properties of biological systems and predict their form and function, including research to accelerate drug discovery for COVID-19. Photo credit: Jason Richards, Oak Ridge National Laboratory, U.S. Dept. of Energy.](/sites/default/files/styles/list_page_thumbnail/public/2020-07/2017-P06162Cropped.jpg?h=f1d4573a&itok=TrvR_opt)
Ada Sedova’s journey to Oak Ridge National Laboratory has taken her on the path from pre-med studies in college to an accelerated graduate career in mathematics and biophysics and now to the intersection of computational science and biology
![Researchers at DOE’s Manufacturing Demonstration Facility at ORNL developed a reusable face mask prototype with injection molding that will enable industry to rapidly manufacture. Credit: Carlos Jones/Oak Ridge National Laboratory, U.S. Dept. of Energy](/sites/default/files/styles/list_page_thumbnail/public/2020-05/2020-P03026_0.jpg?h=5d08f34f&itok=CbBMXqMW)
In the fight against the COVID-19 pandemic, it’s a race against the clock not only to find a vaccine but also to supply healthcare workers with life-saving equipment such as face shields, masks and test kits.
![Alex Johs at ORNL's Spallation Neutron Source](/sites/default/files/styles/list_page_thumbnail/public/2019-06/2019-p01807.jpg?h=f8570409&itok=KBUOueeI)
Sometimes solutions to the biggest problems can be found in the smallest details. The work of biochemist Alex Johs at Oak Ridge National Laboratory bears this out, as he focuses on understanding protein structures and molecular interactions to resolve complex global problems like the spread of mercury pollution in waterways and the food supply.
![Methanogen_mercury_study3.jpg Methanogen_mercury_study3.jpg](/sites/default/files/styles/list_page_thumbnail/public/Methanogen_mercury_study3.jpg?itok=a79hsOOv)
Biologists from Oak Ridge National Laboratory and the Smithsonian Environmental Research Center have confirmed that microorganisms called methanogens can transform mercury into the neurotoxin methylmercury with varying efficiency across species.
![Methanotroph_OB3b_cells Methanotroph_OB3b_cells](/sites/default/files/styles/list_page_thumbnail/public/Methanotroph_OB3b_cells_2.jpg?itok=Iml9vTIS)
A team led by the Department of Energy’s Oak Ridge National Laboratory has identified a novel microbial process that can break down toxic methylmercury in the environment, a fundamental scientific discovery that could potentially reduce mercury toxicity levels and sup...