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An illustration shows how the composite is pressed into a seamless aluminum liner, which is then sealed with an aluminum powder cap. The research is sponsored by the DOE Isotope Program. Credit: Chris Orosco/ORNL, U.S. Dept. of Energy

Oak Ridge National Laboratory researchers have developed a method to simplify one step of radioisotope production — and it’s faster and safer.

Genetic analysis revealed connections between inflammatory activity and development of atomic dermatitis, according to researchers from the UPenn School of Medicine, the Perelman School of Medicine, and Oak Ridge National Laboratory. Credit: Kang Ko/UPenn

University of Pennsylvania researchers called on computational systems biology expertise at Oak Ridge National Laboratory to analyze large datasets of single-cell RNA sequencing from skin samples afflicted with atopic dermatitis.

An ORNL-led team comprising researchers from multiple DOE national laboratories is using artificial intelligence and computational screening techniques – in combination with experimental validation – to identify and design five promising drug therapy approaches to target the SARS-CoV-2 virus. Credit: Michelle Lehman/ORNL, U.S. Dept. of Energy

An ORNL-led team comprising researchers from multiple DOE national laboratories is using artificial intelligence and computational screening techniques – in combination with experimental validation – to identify and design five promising drug therapy approaches to target the SARS-CoV-2 virus.

A radiologist outfitted with the team’s head-mounted eye-tracking device examines a mammogram. Credit: Hong-Jun Yoon/Oak Ridge National Laboratory, U.S. Dept. of Energy

In an effort to reduce errors in the analyses of diagnostic images by health professionals, a team of researchers from the Department of Energy’s Oak Ridge National Laboratory has improved understanding of the cognitive processes 

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For many scientists and engineers, the first real test of their mettle comes not in a classroom, but in a lab or the field, where hands-on experience can teach volumes. For Susan Hogle, that hands-on experience just happened to be with material that was too hot to handle—literally....

By producing 50 grams of plutonium-238, Oak Ridge National Laboratory researchers have demonstrated the nation’s ability to provide a valuable energy source for deep space missions.

With the production of 50 grams of plutonium-238, researchers at the Department of Energy’s Oak Ridge National Laboratory have restored a U.S. capability dormant for nearly 30 years and set the course to provide power for NASA and other missions.

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The probe of an atomic force microscope (AFM) scans a surface to reveal details at a resolution 1,000 times greater than that of an optical microscope. That makes AFM the premier tool for analyzing physical features, but it cannot tell scientists anything about chemistry. For that they turn to the mass spectrometer (MS).
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From the bluebird painting propped against her office wall and the deer she mentions seeing outside her office window, Linda Lewis might be mistaken for a wildlife biologist at first glance. But rather than trailing animal tracks, Lewis, a researcher at the Department of Energy’s Oak Ridge National Laboratory, is more interested in marks left behind by humans.

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With more than 30 patents, James Klett is no stranger to success, but perhaps the Oak Ridge National Laboratory researcher’s most noteworthy achievement didn’t start out so hot – or so it seemed at the time.

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Graphene, a strong, lightweight carbon honeycombed structure that’s only one atom thick, holds great promise for energy research and development. Recently scientists with the Fluid Interface Reactions, Structures, and Transport (FIRST) Energy Frontier Research Center (EFRC), led by the US Department of Energy’s Oak Ridge National Laboratory, revealed graphene can serve as a proton-selective permeable membrane, providing a new basis for streamlined and more efficient energy technologies such as improved fuel cells.