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The AI agent, incorporating a language model-based molecular generator and a graph neural network-based molecular property predictor, processes a set of user-provided molecules (green) and produces/suggests new molecules (red) with desired chemical/physical properties (i.e. excitation energy). Image credit: Pilsun You, Jason Smith/ORNL, U.S. DOE

A team of computational scientists at ORNL has generated and released datasets of unprecedented scale that provide the ultraviolet visible spectral properties of over 10 million organic molecules. 

2023 Battelle Distinguished Inventors

Four scientists affiliated with ORNL were named Battelle Distinguished Inventors during the lab’s annual Innovation Awards on Dec. 1 in recognition of being granted 14 or more United States patents.

Susan Hubbard, ORNL’s deputy for science and technology and Quincy Quick, TSU’s associate vice president for Research and Sponsored Programs, sign a memorandum of understanding to strengthen research cooperation and provide diverse undergraduate students enriching educational research opportunities at the lab. Credit: Carlos Jones/ORNL, U.S. Dept. of Energy

The Department of Energy’s Oak Ridge National Laboratory and Tennessee State University have signed a memorandum of understanding to strengthen research cooperation and provide diverse undergraduate students enriching educational research opportunities at the lab.

Susan Hubbard, ORNL’s deputy for science and technology and Can (John) Saygin, senior vice president for research and dean of the graduate college at UTRGV, sign a memorandum of understanding to strengthen research cooperation and establish a collaborative program for undergraduate research and education. Credit: Carlos Jones/ORNL, U.S. Dept. of Energy

ORNL and the University of Texas Rio Grande Valley, known as UTRGV, have signed a memorandum of understanding to strengthen research cooperation and establish a collaborative program for undergraduate research and education, further cementing hi

Susan Hubbard, diputada de Ciencia y Tecnología en ORNL, Can (John) Saygin, vicepresidente mayor de investigación y decano del Colegio de la Escuela de Postgrados en UTGRV, firman un Memorándum de Entendimiento comprometiéndose a fortalecer la cooperación en la investigación científica y establecer un programa colaborativo para estudiantes de pregrado. Crédito de la fotografía: Carlos Jones/ORNL, U.S. Dept. of Energy

Susan Hubbard, diputada de Ciencia y Tecnología en ORNL, Can (John) Saygin, vicepresidente mayor de investigación y decano del Colegio de la Escuela de Postgrados en UTGRV, firman un Memorándum de Entendimiento comprometiéndose a fortalecer

Scientists conducted microbial DNA sampling at a Yellowstone National Park hot spring for a study sponsored by DOE’s Biological and Environmental Research program, the National Science Foundation and NASA. Credit: Mircea Podar/ORNL, U.S. Dept. of Energy

Oak Ridge National Laboratory scientists studied hot springs on different continents and found similarities in how some microbes adapted despite their geographic diversity.

ORNL researchers, from left, Yang Liu, Xiaohan Yang and Torik Islam, collaborated on the development of a new capability to insert multiple genes simultaneously for fast, efficient transformation of plants into better bioenergy feedstocks. Credit: Genevieve Martin/ORNL, U.S. Dept. of Energy

In a discovery aimed at accelerating the development of process-advantaged crops for jet biofuels, scientists at ORNL developed a capability to insert multiple genes into plants in a single step.

ORNL scientists mutated amino acids in a receptor protein, shown in green, which diminished interaction with the SARS-CoV-2 virus spike protein, shown in red. Mutating the receptor protein hampered the virus’s ability to infect host cells. Credit: ORNL, U.S. Dept. of Energy

Oak Ridge National Laboratory scientists exploring bioenergy plant genetics have made a surprising discovery: a protein domain that could lead to new COVID-19 treatments.

Oak Ridge National Laboratory led a team of scientists to design a molecule that disrupts the infection mechanism of the SARS-CoV-2 coronavirus and could be used to develop new treatments for COVID-19 and future virus outbreaks. Credit: Michelle Lehman/ORNL, U.S. Dept. of Energy

A team of scientists led by the Department of Energy’s Oak Ridge National Laboratory designed a molecule that disrupts the infection mechanism of the SARS-CoV-2 coronavirus and could be used to develop new treatments for COVID-19 and other viral diseases.