Case closed: Neutrons settle 40-year debate on enzyme for drug design
Scientists at ORNL used neutrons to end a decades-long debate about an enzyme cancer uses.
After retiring from Y-12, Scott Abston joined the Isotope Science and Engineering Directorate to support isotope production and work with his former manager. He now leads a team maintaining critical equipment for medical and space applications. Abston finds fulfillment in mentoring his team and is pleased with his decision to continue working.
Jeremiah Sewell leads a team at ORNL, working on xenon-129 production for lung imaging. Reflecting on his career, Sewell views each opportunity as a "door" he steps through, leveraging over 25 years of experience in nuclear power and centrifuge operations to advance the facility’s mission.
Debjani Singh, a senior scientist at ORNL, leads the HydroSource project, which enhances hydropower research by making water data more accessible and useful. With a background in water resources, data science, and earth science, Singh applies innovative tools like AI to advance research. Her career, shaped by her early exposure to science in India, focuses on bridging research with practical applications.
At ORNL, a group of scientists used neutron scattering techniques to investigate a relatively new functional material called a Weyl semimetal. These Weyl fermions move very quickly in a material and can carry electrical charge at room temperature. Scientists think that Weyl semimetals, if used in future electronics, could allow electricity to flow more efficiently and enable more energy-efficient computers and other electronic devices.
Brian Sanders is focused on impactful, multidisciplinary science at Oak Ridge National Laboratory, developing solutions for everything from improved imaging of plant-microbe interactions that influence ecosystem health to advancing new treatments for cancer and viral infections.
ORNL's Guang Yang and Andrew Westover have been selected to join the first cohort of DOE’s Advanced Research Projects Agency-Energy Inspiring Generations of New Innovators to Impact Technologies in Energy 2024 program. The program supports early career scientists and engineers in their work to convert disruptive ideas into impactful energy technologies.
Researchers set a new benchmark for future experiments making materials in space rather than for space. They discovered that many kinds of glass have similar atomic structure and arrangements and can successfully be made in space. Scientists from nine institutions in government, academia and industry participated in this 5-year study.
Researchers tackling national security challenges at ORNL are upholding an 80-year legacy of leadership in all things nuclear. Today, they’re developing the next generation of technologies that will help reduce global nuclear risk and enable safe, secure, peaceful use of nuclear materials, worldwide.
The BIO-SANS instrument, located at Oak Ridge National Laboratory’s High Flux Isotope Reactor, is the latest neutron scattering instrument to be retrofitted with state-of-the-art robotics and custom software. The sophisticated upgrade quadruples the number of samples the instrument can measure automatically and significantly reduces the need for human assistance.