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Computational biophysicist Ada Sedova is using experiments and high-performance computing to explore the properties of biological systems and predict their form and function, including research to accelerate drug discovery for COVID-19. Photo credit: Jason Richards, Oak Ridge National Laboratory, U.S. Dept. of Energy.

Ada Sedova’s journey to Oak Ridge National Laboratory has taken her on the path from pre-med studies in college to an accelerated graduate career in mathematics and biophysics and now to the intersection of computational science and biology

ORNL scientists are currently using Proto-MPEX to perform necessary research and development that is needed to build MPEX. Credit: Genevieve Martin/Oak Ridge National Laboratory, U.S. Dept. of Energy

Temperatures hotter than the center of the sun. Magnetic fields hundreds of thousands of times stronger than the earth’s. Neutrons energetic enough to change the structure of a material entirely.

Using the single-crystal diffractometer TOPAZ, Oak Ridge National Laboratory confirmed the exact position of deuterium atoms from selective deuteration of benzene molecules. Credit: Oak Ridge National Laboratory, U.S. Dept. of Energy

Scientists have found a new method to strategically add deuterium to benzene, an aromatic compound commonly found in crude oil. When applied to the active ingredient of drugs to incorporate deuterium, it could dramatically improve the drugs’ efficacy and safety and even introduce new medicines.

Solid radium sulfate sits in the bottom of a flask during the recovery process. Credit: Oak Ridge National Laboratory, U.S. Dept. of Energy

Oak Ridge National Laboratory researchers have discovered a better way to separate actinium-227, a rare isotope essential for an FDA-approved cancer treatment.

The 1250 ton cyrostat base is positioned over the ITER tokamak pit for installation. This base is the heaviest lift of tokamak assembly. Credit: ITER Organization

ITER, the world’s largest international scientific collaboration, is beginning assembly of the fusion reactor tokamak that will include 12 different essential hardware systems provided by US ITER, which is managed by Oak Ridge National Laboratory.

Recent research involving Oak Ridge National Laboratory’s Spallation Neutron Source demonstrates crystal-like heat conduction in a solid-liquid hybrid, AgCrSe2.

Research by an international team led by Duke University and the Department of Energy’s Oak Ridge National Laboratory scientists could speed the way to safer rechargeable batteries for consumer electronics such as laptops and cellphones.

Omar Demerdash

With the rise of the global pandemic, Omar Demerdash, a Liane B. Russell Distinguished Staff Fellow at ORNL since 2018, has become laser-focused on potential avenues to COVID-19 therapies.

Batteries - The 3D connection

Oak Ridge National Laboratory researchers have developed a thin film, highly conductive solid-state electrolyte made of a polymer and ceramic-based composite for lithium metal batteries.

Computing – Mining for COVID-19 connections

Scientists have tapped the immense power of the Summit supercomputer at Oak Ridge National Laboratory to comb through millions of medical journal articles to identify potential vaccines, drugs and effective measures that could suppress or stop the spread of COVID-19.

Catherine Schuman, top right, spoke to Copper Ridge Elementary School fifth graders about her job as an ORNL computer scientist as part of the lab’s STEM outreach during the COVID-19 pandemic. Credit: Abby Bower/Oak Ridge National Laboratory, U.S. Dept. of Energy

With Tennessee schools online for the rest of the school year, researchers at ORNL are making remote learning more engaging by “Zooming” into virtual classrooms to tell students about their science and their work at a national laboratory.