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Director of ORNL’s AI Initiative Prasanna Balaprakash addresses attendees at the Generative AI for ORNL Science Workshop. Credit: ORNL, U.S. Dept. of Energy

The Department of Energy’s Oak Ridge National Laboratory hosted its Smoky Mountains Computational Science and Engineering Conference for the first time in person since the COVID pandemic broke in 2020. The conference, which celebrated its 20th consecutive year, took place at the Crowne Plaza Hotel in downtown Knoxville, Tenn., in late August.

Steve Nolan, left, who manages many ORNL facilities for United Cleanup Oak Ridge, and Carl Dukes worked closely together to accommodate bringing members of the public into the Oak Ridge Reservation to collect distant images from overhead for the BRIAR biometric recognition project. Credit: Carlos Jones/ORNL, U.S. Dept. of Energy

Carl Dukes’ career as an adept communicator got off to a slow start: He was about 5 years old when he spoke for the first time. “I’ve been making up for lost time ever since,” joked Dukes, a technical professional at the Department of Energy’s Oak Ridge National Laboratory.

ORNL researchers encoded grid hardware operating data into a color band hidden inside photographs, video or artwork, as shown in this photo. The visual can then be transmitted to a utility’s control center for decoding. Credit: ORNL/U.S. Dept. of Energy

Inspired by one of the mysteries of human perception, an ORNL researcher invented a new way to hide sensitive electric grid information from cyberattack: within a constantly changing color palette.

From left to right, Cortney Piper, executive director of the Tennessee Advanced Energy Business Council; Susan Hubbard, ORNL deputy for science and technology; Dan Miller, innovation Crossroads program lead; and Mike Paulus, ORNL director of technology transfer, attend the Innovation Crossroads Showcase at the Knoxville Chamber on Sept. 22. Credit: Carlos Jones/ORNL, U.S. Dept. of Energy

A crowd of investors and supporters turned out for last week’s Innovation Crossroads Showcase at the Knoxville Chamber as part of Innov865 Week. Sponsored by ORNL and the Tennessee Advanced Energy Business Council, the event celebrated deep-tech entrepreneurs and the Oak Ridge Corridor as a growing energy innovation hub for the nation.

ORNL, VA and Harvard researchers developed a sparse matrix full of anonymized information on what is thought to be the largest cohort of healthcare data used for this type of research in the U.S. The matrix can be probed with different methods, such as KESER, to gain new insights into human health. Credit: Nathan Armistead/ORNL, U.S. Dept. of Energy

A team of researchers has developed a novel, machine learning–based  technique to explore and identify relationships among medical concepts using electronic health record data across multiple healthcare providers.

Genetic analysis revealed connections between inflammatory activity and development of atomic dermatitis, according to researchers from the UPenn School of Medicine, the Perelman School of Medicine, and Oak Ridge National Laboratory. Credit: Kang Ko/UPenn

University of Pennsylvania researchers called on computational systems biology expertise at Oak Ridge National Laboratory to analyze large datasets of single-cell RNA sequencing from skin samples afflicted with atopic dermatitis.

An ORNL-led team studied the SARS-CoV-2 spike protein in the trimer state, shown here, to pinpoint structural transitions that could be disrupted to destabilize the protein and negate its harmful effects. Credit: Debsindhu Bhowmik/ORNL, U.S. Dept. of Energy

To explore the inner workings of severe acute respiratory syndrome coronavirus 2, or SARS-CoV-2, researchers from ORNL developed a novel technique.

An ORNL-led team comprising researchers from multiple DOE national laboratories is using artificial intelligence and computational screening techniques – in combination with experimental validation – to identify and design five promising drug therapy approaches to target the SARS-CoV-2 virus. Credit: Michelle Lehman/ORNL, U.S. Dept. of Energy

An ORNL-led team comprising researchers from multiple DOE national laboratories is using artificial intelligence and computational screening techniques – in combination with experimental validation – to identify and design five promising drug therapy approaches to target the SARS-CoV-2 virus.

Verónica Melesse Vergara speaks with third and fourth graders at East Side Intermediate School in Brownsville. Credit: ORNL, U.S. Dept. of Energy

Twenty-seven ORNL researchers Zoomed into 11 middle schools across Tennessee during the annual Engineers Week in February. East Tennessee schools throughout Oak Ridge and Roane, Sevier, Blount and Loudon counties participated, with three West Tennessee schools joining in.

ORNL researchers in advanced manufacturing, materials science and engineering collaborated to produce face shields and reusable mask molds so that industry can quickly mass produce. Credit: Carlos Jones/Oak Ridge National Laboratory, U.S. Dept. of Energy

The University of Texas at San Antonio (UTSA) has formally launched the Cybersecurity Manufacturing Innovation Institute (CyManII), a $111 million public-private partnership.