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To better understand how the novel coronavirus behaves and how it can be stopped, scientists have completed a three-dimensional map that reveals the location of every atom in an enzyme molecule critical to SARS-CoV-2 reproduction.

Geoffrey L. Greene, a professor at the University of Tennessee, Knoxville, who holds a joint appointment with ORNL, will be awarded the 2021 Tom Bonner Prize for Nuclear Physics from the American Physical Society.

Through a one-of-a-kind experiment at ORNL, nuclear physicists have precisely measured the weak interaction between protons and neutrons. The result quantifies the weak force theory as predicted by the Standard Model of Particle Physics.

Pick your poison. It can be deadly for good reasons such as protecting crops from harmful insects or fighting parasite infection as medicine — or for evil as a weapon for bioterrorism. Or, in extremely diluted amounts, it can be used to enhance beauty.

A team of researchers has performed the first room-temperature X-ray measurements on the SARS-CoV-2 main protease — the enzyme that enables the virus to reproduce.

In the race to identify solutions to the COVID-19 pandemic, researchers at the Department of Energy’s Oak Ridge National Laboratory are joining the fight by applying expertise in computational science, advanced manufacturing, data science and neutron science.

A versatile class of flexible, protein-like polymers could significantly advance future drug delivery methods. But first, scientists have to develop a reliable process for tailoring these polymers into shapes that can effectively transport medicines throughout the human body.

Biological membranes, such as the “walls” of most types of living cells, primarily consist of a double layer of lipids, or “lipid bilayer,” that forms the structure, and a variety of embedded and attached proteins with highly specialized functions, including proteins that rapidly and selectively transport ions and molecules in and out of the cell.

A team of scientists has for the first time measured the elusive weak interaction between protons and neutrons in the nucleus of an atom. They had chosen the simplest nucleus consisting of one neutron and one proton for the study.

To learn more about interactions between drug molecules and micelles, Associate Professor Megan Robertson and graduate students Tyler Cooksey and Tzu-Han Li from the University of Houston (UH) are using neutrons at the Department of Energy’s (DOE’s) Oak Ridge National Laboratory (ORNL).