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OAK RIDGE, Tenn., March 20, 2019—Direct observations of the structure and catalytic mechanism of a prototypical kinase enzyme—protein kinase A or PKA—will provide researchers and drug developers with significantly enhanced abilities to understand and treat fatal diseases and neurological disorders such as cancer, diabetes, and cystic fibrosis.
As the rise of antibiotic-resistant bacteria known as superbugs threatens public health, Oak Ridge National Laboratory’s Shuo Qian and Veerendra Sharma from the Bhaba Atomic Research Centre in India are using neutron scattering to study how an antibacterial peptide interacts with and fights harmful bacteria.
Oak Ridge National Laboratory is using ultrasonic additive manufacturing to embed highly accurate fiber optic sensors in heat- and radiation-resistant materials, allowing for real-time monitoring that could lead to greater insights and safer reactors.
By automating the production of neptunium oxide-aluminum pellets, Oak Ridge National Laboratory scientists have eliminated a key bottleneck when producing plutonium-238 used by NASA to fuel deep space exploration.
With the production of 50 grams of plutonium-238, researchers at the Department of Energy’s Oak Ridge National Laboratory have restored a U.S. capability dormant for nearly 30 years and set the course to provide power for NASA and other missions.
When it’s up and running, the ITER fusion reactor will be very big and very hot, with more than 800 cubic meters of hydrogen plasma reaching 170 million degrees centigrade. The systems that fuel and control it, on the other hand, will be small and very cold. Pellets of frozen gas will be shot int...