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The quality and quantity of refrigerant charge in any vapor compression-based heating and cooling system is vital to its energy efficiency, thermal capacity, and reliability.

Performance of heat exchangers greatly suffers due to maldistribution of fluid, which also impacts the performance of the entire HVAC system. One method to reduce fluid maldistribution is to improve the design of the manifold to make the flow evenly distributed.

High and ultra-high vacuum applications require seals that do not allow leaks. O-rings can break down over time, due to aging and exposure to radiation. Metallic seals can damage sealing surfaces, making replacement of the original seal very difficult.

Moisture management accounts for over 40% of the energy used by buildings. As such development of energy efficient and resilient dehumidification technologies are critical to decarbonize the building energy sector.

ORNL has developed a new thermal energy storage design utilizing low conductivity organic phase change materials.

Household refrigerators typically consume 1.5–2.0kWh of electricity per day, and more than 100 million refrigerators are used in US homes, resulting in significant primary energy consumption and carbon emissions.